Research
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Areas of Research
Biosystems and Health

Advancing basic and translational research to address critical healthcare issues and answer fundamental biological questions at scales from molecules to systems

From molecular mechanics to multiscale physiological simulations to the control of prosthetic limbs, mechanical engineering helps develop technologies that improve human health and offers insights into fundamental biological processes. In close collaboration with the Feinberg School of Medicine and the Shirley Ryan AbilityLab, the nation's #1 rehabilitation research hospital, we address pressing healthcare challenges.

View biosystems and health faculty

Research Area Subtopics

Brenna Argall
Robotics intelligence added to powered wheelchairs can
improve safety. (B. Argall)

Human-robot Systems

Design of effective human-robot systems requires a deep understanding of human motor control and psychophysics. Working with our partners at the medical school and the Shirley Ryan AbilityLab, we are advancing the state of the art in human-robot systems in areas such as haptic interfaces, advanced prosthetics, rehabilitation robots, and robots for safe physical collaboration with humans (“cobots,” a term coined in our department).



Hybrid electronic/microfluidic device architecture for stretchable radios (F. Frankel)
Hybrid electronic/microfluidic device architecture for
stretchable radios. (F. Frankel, J. Rogers)

Bioelectronics

Bioelectronic devices enable the transparent integration of flexible, biological tissue with silicon-based electronics. Applications of this interface of biology with technology are numerous, including wireless skin-like wearable sensors and actuators, resorbable electronics, and targeted drug delivery.






Integrating engineering technologies for personalized medicine (H.D. Espinosa, J. Kessler, and P. Mukherjee)
Integrating engineering technologies for personalized
medicine. (H.D. Espinosa, J. Kessler, and P. Mukherjee)

Cell Therapy

We are advancing the science and engineering of integrated microfluidic platforms for gene editing and live cell analysis. By combining single-cell RNA sequencing and machine learning lineage tracing with non-destructive temporal measurement of signaling proteins, an unprecedented detailed molecular landscape of desired lineage specifications is being constructed. We target applications in disease modeling, drug screening, immunology, and other cell therapies.



Understanding cell mechanics with atomic force microscopy (H.D. Espinosa and K. Green)
Understanding cell mechanics with atomic force
microscopy. (H.D. Espinosa, K. Green)

Mechanics of Biosystems

New computational methods are being developed to study complex dynamics of biological systems to better understand biological processes and treat diseases. We aim to shift the existing paradigm of studying disease pathogenesis of organs toward a biomechanics-based approach. We aspire to create new phenotypic classifications and diagnostic platforms with a focus on quantitative mechanics-based physiomarkers (esophagus, heart, lungs).




Robotic System Identification for a Functional Electrical Stimulation Neuroprosthesis (K. Lynch and E. Schearer)
Robotic system identification for a functional electrical
stimulation neuroprosthesis. (K. Lynch, E. Schearer)

Sensorimotor Control

Using approaches including neuromechanics, information theory, neurophysiology, psychophysics, and synthetic data generation, our work aims to reveal fundamental sensorimotor principles that guide perception, action, and cognition in humans and animals, and to apply these principles to the design and control of novel robots and assistive devices.



ME Faculty

Photo of Brenna Argall

Brenna Argall

Associate Professor of Computer Science

Associate Professor of Mechanical Engineering

Associate Professor of Physical Medicine and Rehabilitation

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Oluwaseyi Balogun

Associate Professor of Civil and Environmental Engineering and Mechanical Engineering

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J. Edward Colgate

Walter P. Murphy Professor of Mechanical Engineering

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Horacio Espinosa

James N. and Nancy J. Farley Professor in Manufacturing & Entrepreneurship

Director, Theoretical and Applied Mechanics Program

Director of the Institute for Cellular Engineering Technologies

Professor of Mechanical Engineering and (by courtesy) Biomedical Engineering and Civil and Environmental Engineering

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Mitra Hartmann

Professor of Biomedical Engineering

Professor of Mechanical Engineering

Professor of Computer Science (by courtesy)

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Yonggang Huang

Jan and Marcia Achenbach Professorship in Mechanical Engineering, Civil and Environmental Engineering, and (by courtesy) Materials Science and Engineering

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Sinan Keten

Jerome B. Cohen Professor of Engineering

Professor of Mechanical Engineering and Civil and Environmental Engineering and (by courtesy) Biomedical Engineering

Associate Chair of Mechanical Engineering

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Kevin Lynch

Professor of Mechanical Engineering

Director, Center for Robotics and Biosystems

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Malcolm MacIver

Professor of Biomedical Engineering

Professor of Mechanical Engineering

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Todd Murphey

Professor of Mechanical Engineering

Director of the Master of Science in Robotics Program

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K.-C. Kenneth Park

Assistant Professor of Mechanical Engineering

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Neelesh Patankar

Professor of Mechanical Engineering and (by courtesy) Engineering Sciences and Applied Mathematics

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Michael Peshkin

Professor of Mechanical Engineering

Allen K. and Johnnie Cordell Breed Senior Professor in Design

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Cheng Sun

Professor of Mechanical Engineering

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Ryan Truby

Assistant Professor of Materials Science and Engineering

Assistant Professor of Mechanical Engineering

June and Donald Brewer Junior Professor

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Gregory Wagner

Associate Professor of Mechanical Engineering

Bette and Neison Harris Chair in Teaching Excellence

Director of Graduate Studies for Mechanical Engineering

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Courtesy Faculty

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Ange-Therese Akono

Adjunct Assistant Professor of Civil and Environmental Engineering

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Mark Johnson

Professor of Biomedical Engineering

Professor of Mechanical Engineering (by courtesy)

Professor of Ophthalmology (by courtesy)

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Michael Miksis

Professor of Engineering Sciences and Applied Mathematics and (by courtesy) Mechanical Engineering

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Aaron Packman

Professor of Civil and Environmental Engineering and (by courtesy) Mechanical Engineering and Chemical and Biological Engineering

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John Rogers

Louis Simpson and Kimberly Querrey Professor of Materials Science and Engineering, Biomedical Engineering and Neurological Surgery (and by courtesy Electrical and Computer Engineering, Mechanical Engineering, Chemistry and Dermatology)

Director, Querrey Simpson Institute for Bioelectronics

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Petia Vlahovska

Professor of Engineering Sciences and Applied Mathematics (by courtesy) Mechanical Engineering

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