Faculty Directory
Joseph Moskal

Professor of Biomedical Engineering

Professor of Neurological Surgery (MED)

Director of the Falk Center for Molecular Therapeutics


2145 Sheridan Road
Evanston, IL 60208-3109

Email Joseph Moskal


Falk Center for Molecular Therapeutics


Biomedical Engineering

Research Interests

Pharmacogenomics, Drug Discovery, Brain Tumor Therapeutics

Selected Publications

  • Burgdorf, Jeffrey S.; Yoon, Sehyoun; Dos Santos, Marc; Lammert, Catherine R.; Moskal, Joseph R.; Penzes, Peter, An IGFBP2-derived peptide promotes neuroplasticity and rescues deficits in a mouse model of Phelan-McDermid syndrome, Molecular Psychiatry (2023).
  • Burgdorf, Jeffrey S.; Zhang, Xiao Lei; Stanton, Patric K.; Moskal, Joseph R.; Donello, John E., Zelquistinel Is an Orally Bioavailable Novel NMDA Receptor Allosteric Modulator That Exhibits Rapid and Sustained Antidepressant-Like Effects, International Journal of Neuropsychopharmacology (2022).
  • Zhang, Xiao Lei; Berglund, Nils A.; Burgdorf, Jeffrey S.; Donello, John E.; Moskal, Joseph R.; Stanton, Patric K., Extracellular application of the N-methyl-D-aspartate receptor allosteric modulator rapastinel acts remotely to regulate Ca2+inactivation at an intracellular locus, Neuroreport (2022).
  • Basu, Subhash C.; Agarwal, Arun K.; Basu, Manju; Ma, Rui; Moskal, Joseph R., Stereo-specific glycomic codes of the normal and metastatic cancer cell surfaces, Nova Science Publishers, Inc.:177-200 (2021).
  • Barth, A. L.; Schneider, J. S.; Johnston, T. H.; Hill, M. P.; Brotchie, J. M.; Moskal, J. R.; Cearley, Cassia N., NYX-458 Improves Cognitive Performance in a Primate Parkinson's Disease Model, Movement Disorders 35(4):640-649 (2020).
  • Burgdorf, J. S.; Brudzynski, S. M.; Moskal, J. R., Using rat ultrasonic vocalization to study the neurobiology of emotion, Current opinion in neurobiology 60:192-200 (2020).
  • Morrison, Gladys; Asiedu, Marina N.; Priebe, Jessica M.; Dunning, Jacqueline; Ghoreishi-Haack, Nayereh; Kroes, Roger A.; Bowers, M. Scott; Barth, Amanda L.; Cearley, Cassia N.; Moskal, Joseph R., The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC, Neurobiology of Pain 7 (2020).
  • Burgdorf, Jeffrey S.; Vitaterna, Martha H.; Olker, Christopher J.; Song, Eun Joo; Christian, Edward P.; Sørensen, Laurits; Turek, Fred W.; Madsen, Torsten M.; Khan, M. Amin; Kroes, Roger A.; Moskal, Joseph R., NMDAR activation regulates the daily rhythms of sleep and mood, Sleep 42(10) (2019).