Faculty Directory
Chad Mirkin

George B. Rathmann Professor of Chemistry, Materials Science and Engineering, and (by courtesy) Chemical and Biological Engineering and Biomedical Engineering

Director, International Institute for Nanotechnology


2190 Campus Drive
Ryan Hall, Room 3010
Evanston, IL 60208

847-467-7302Email Chad Mirkin


Mirkin Research Group


Materials Science and Engineering

Chemical and Biological Engineering

Biomedical Engineering


PhD Program in Interdisciplinary Biological Sciences


NSF Postdoctoral Fellow in Chemistry, MIT, Cambridge, MA

Ph.D. Organic Chemistry, Penn State, State College, PA

B.S. Chemistry (Phi Beta Kappa), Dickinson College, Carlisle, PA

Research Interests

Fundamental and applied nanoscience, nanomaterials, nanibiotechnology, nanomedicine, nanolithography

Our research focuses on developing methods for controlling the architecture of molecules and materials on the 1-100 nm length scale, and utilizing such structures in the development of analytical tools that can be used in the areas of chemical and biological sensing, lithography, catalysis, and optics.

Mirkin has pioneered the use of biomolecules as synthons in materials science and the development of nanoparticle-based biodiagnostics. Many of the concepts and materials developed within his laboratories are now the basis for commercial detection and lithography systems.

Significant Recognition

  • 2022 Acta Biomaterialia Gold Medal
  • 2021 De Gennes Prize, Royal Society of Chemistry
  • 2021 G.M. Kosolapoff Award
  • 2020 AAAS Philip Hauge Abelson Prize
  • 2019 Kabiller Prize in Nanoscience and Nanomedicine
  • 2019 Perkin Medal
  • 2019 Netherlands Award for Supramolecular Chemistry
  • 2018 Theodore William Richards Medal
  • 2018 Remsen Award
  • 2018 Ralph N. Adams Award in Bioanalytical Chemistry
  • 2017 Fellow, American Chemical Society
  • 2017 Wilhelm Exner Medal
  • 2017 Dickson Prize in Science
  • 2017 William H. Nichols Medal
  • 2016 Dan David Prize
  • 2016 American Institute of Chemists Gold Medal
  • 2015 Fellow, American Institute for Medical and Biological Engineering
  • 2015 Raymond and Beverly Sackler Prize in Convergence Research
  • 2015 Royal Society of Chemistry (RSC) Centenary Prize
  • 2013 Fellow, National Academy of Inventors
  • 2013 Linus Pauling Medal
  • 2013 Walston Chubb Award for Innovation
  • 2012 American Chemical Society Award for Creative Invention
  • 2011 Fellow, American Academy of Arts and Sciences
  • 2010 Fellow, National Academy of Medicine
  • 2010 Fellow, National Academy of Sciences
  • 2009 $500,000 Lemelson-MIT Prize
  • 2009 Member, President’s Council of Advisors on Science & Technology (PCAST, Obama Administration)
  • 2009 Fellow, National Academy of Engineering

Significant Professional Service

  • National Academy of Engineering
  • Editorial Advisory Board of Accounts of Chemical Research
  • Editorial Advisory Board, Advanced Materials
  • Editorial Advisory Board, Chemical and Engineering News
  • Editorial Advisory Board, BioMacromolecules
  • Editorial Advisory Board, Macromolecular Bioscience
  • Editorial Advisory Board, SENSORS
  • Editorial Advisory Board, Encyclopedia of Nanoscience and Nanotechnology
  • Editorial Advisory Board, Chemistry-A European Journal
  • Editorial Advisory Board, Macro-Journals of Macromolecule
  • Editorial Advisory Board, Chemistry & Biology
  • Editorial Advisory Board, Nanotechnology Law & Business
  • Editorial Advisory Board, Journal of Materials Chemistry
  • Editorial Advisory Board, Journal of Cluster Science
  • Founding editor of the journal Small
  • Science Advisory Board member for the International Society for Nanoscale Science, Computation and Engineering

Selected Publications

  • Sinegra, Andrew J.; Evangelopoulos, Michael; Park, Jungsoo; Huang, Ziyin; Mirkin, Chad A., Lipid Nanoparticle Spherical Nucleic Acids for Intracellular DNA and RNA Delivery, Nano letters 21(15):6584-6591.
  • Miao, Ziyi; Zheng, Cindy Y.; Schatz, George C.; Lee, Byeongdu; Mirkin, Chad A., Low-Density 2D Superlattices Assembled via Directional DNA Bonding, Angewandte Chemie - International Edition 60(35):19035-19040.
  • Huang, Ziyin N.; Callmann, Cassandra E.; Cole, Lisa E.; Wang, Shuya; Mirkin, Chad A., Synergistic Immunostimulation through the Dual Activation of Toll-like Receptor 3/9 with Spherical Nucleic Acids, ACS nano 15(8):13329-13338.
  • Ebrahimi, Sasha B.; Samanta, Devleena; Partridge, Benjamin E.; Kusmierz, Caroline D.; Cheng, Ho Fung; Grigorescu, Arabela A.; Chávez, Jorge L.; Mirau, Peter A.; Mirkin, Chad A., Programming Fluorogenic DNA Probes for Rapid Detection of Steroids, Angewandte Chemie - International Edition 60(28):15260-15265.
  • Oh, Eun Bi; Golnabi, Rustin; Walker, David A.; Mirkin, Chad A., Electrochemical Polymer Pen Lithography, Small 17(28).
  • Kluender, Edward J.; Bourgeois, Marc R.; Cherqui, Charles R.; Schatz, George C; Mirkin, Chad A., Multimetallic Nanoparticles on Mirrors for SERS Detection, Journal of Physical Chemistry C 125(23):12784-12791.
  • Partridge, Benjamin E.; Winegar, Peter H.; Han, Zhenyu; Mirkin, Chad A., Redefining Protein Interfaces within Protein Single Crystals with DNA, Journal of the American Chemical Society 143(23):8925-8934.
  • Song, Qian; Wang, Xiao Qi; Holmes, Thomas R.; Bonkowski, Michael; Roth, Eric W.; Ponedal, Adam; Mirkin, Chad; Paller, Amy S., Epidermal SR-A Complexes Are Lipid Raft Based and Promote Nucleic Acid Nanoparticle Uptake, Journal of Investigative Dermatology 141(6):1428-1437.e8.