Faculty Directory
Michael Markl

Lester B. and Frances T. Knight Professor of Cardiac Imaging


Northwestern University Feinberg School of Medicine
737 N. Michigan Avenue, Suite 1600
Chicago, IL 60611

312-695-1799 Email Michael Markl


Markl Lab


Biomedical Engineering

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Ph.D., University of Freiburg, 2000

Research Interests

A central objective of Dr. Markl's research program is to develop multi-parametric imaging techniques than can afford a better understanding of the underlying physiologic mechanisms of heart disease and stroke as well as the impact of therapy. The work of his research group has been instrumental in establishing '4D Flow MRI' for the comprehensive assessment of cardiovascular hemodynamics in heart disease and stroke. Further accomplishments include the development, validation, and application of novel imaging tools for the evaluation of structure and function of the heart

Selected Publications

  • Zhang, Jiacheng; Brindise, Melissa C.; Rothenberger, Sean M.; Markl, Michael; Rayz, Vitaliy L.; Vlachos, Pavlos P., A multi-modality approach for enhancing 4D flow magnetic resonance imaging via sparse representation, Journal of the Royal Society Interface (2022).
  • Markl, Michael, Special Issue on 4D Flow MRI in Magnetic Resonance in Medical Sciences, Magnetic Resonance in Medical Sciences (2022).
  • Shahid, Labib; Rice, James; Berhane, Haben; Rigsby, Cynthia; Robinson, Joshua; Griffin, Lindsay; Markl, Michael; Roldán-Alzate, Alejandro, Enhanced 4D Flow MRI-Based CFD with Adaptive Mesh Refinement for Flow Dynamics Assessment in Coarctation of the Aorta, Annals of Biomedical Engineering (2022).
  • Shan, Yan; Li, Jun; Wu, Boting; Barker, Alex J.; Markl, Michael; Lin, Jiang; Shu, Xianhong; Wang, Yongshi, Aortic Viscous Energy Loss for Assessment of Valve-related Hemodynamics in Asymptomatic Severe Aortic Stenosis, Radiology: Cardiothoracic Imaging (2022).
  • Cerne, John W.; Pathrose, Ashitha; Singer, Alyssa M.; Moore, Jackson E.; Serhal, Ali; Aouad, Pascale; Umair, Muhammad; Ragin, Ann; Allen, Bradley D.; Avery, Ryan; Markl, Michael; Carr, James C., MRA of the Supraaortic Vasculature, Journal of Magnetic Resonance Imaging (2022).
  • Jarvis, Kelly; Scott, Michael B.; Soulat, Gilles; Elbaz, Mohammed S.M.; Barker, Alex J.; Carr, James C.; Markl, Michael; Ragin, Ann, Aortic Pulse Wave Velocity Evaluated by 4D Flow MRI Across the Adult Lifespan, Journal of Magnetic Resonance Imaging (2022).
  • Rothenberger, Sean M.; Zhang, Jiacheng; Brindise, Melissa C.; Schnell, Susanne; Markl, Michael; Vlachos, Pavlos P.; Rayz, Vitaliy L., Modeling Bias Error in 4D Flow MRI Velocity Measurements, IEEE Transactions on Medical Imaging (2022).
  • Berhane, Haben; Scott, Michael B.; Barker, Alex J.; McCarthy, Patrick; Avery, Ryan; Allen, Brad; Malaisrie, Chris; Robinson, Joshua D.; Rigsby, Cynthia K.; Markl, Michael, Deep learning–based velocity antialiasing of 4D-flow MRI, Magnetic resonance in medicine (2022).