Faculty Directory
Robert A. Linsenmeier

Professor Emeritus of Biomedical Engineering

Professor Emeritus of Neurobiology

Contact

2145 Sheridan Road
Tech E368
Evanston, IL 60208-3107

Email Robert Linsenmeier

Website

NCEER - Northwestern Center for Engineering Education Research

Laboratory of Robert A. Linsenmeier


Departments

Biomedical Engineering


Education

Post-doc, Northwestern University, Evanston, IL

Post-doc, University of California, San Francisco

PhD Biomedical Engineering, Northwestern University, Evanston, IL

MS Biomedical Engineering, Northwestern University, Evanston, IL

BS Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA


Research Interests

Microenvironment of the mammalian retina, including oxygen and pH regulation, in health and disease; engineering education research.



Significant Recognition

  • Fellow, Association for Research in Vision and Ophthalmology, 2009
  • Fellow, Biomedical Engineering Society, 2005
  • Bette and Neison Harris Professor of Teaching Excellence, Northwestern University 2003 - 2006
  • Fellow, American Institute of Medical and Biological Engineering, 1999

Significant Professional Service

  • Chair, College of Fellows, American Institute of Medical and Biological Engineering, 2010
  • Editor in Chief, Current Eye Research
  • Chair, Third Biomedical Engineering Education Summit Meeting, St. Charles, IL, 2008
  • Vice President, American Institute of Medical and Biological Engineering. 2005-2007

Selected Publications

Education

Cole, J.Y., Linsenmeier, R.A., Miller, T., Glucksberg, M.R. (2012) Using Instruction to Improve Mathematical Modeling in Capstone Design. Proceedings of the American Society for Engineering Education Conference and Exposition. San Antonio, TX, June, https://peer.asee.org/22185

Linsenmeier, R.A. and Gatchell, D.E. (2014) Similarities and Differences in Undergraduate Biomedical Engineering Curricula in the United States. Proceedings of the American Society for Engineering Education Conference and Exposition. Indianapolis, IN. https://peer.asee.org/23015

Baiduc, R.R., Linsenmeier, R.A., and Ruggeri, N. (2015) Mentored Discussions of Teaching: An Introductory Teaching Development Program for Future STEM Faculty.  Innovative Higher Education, published online, 12-Nov-2015  https://doi.org/10.1007/s10755-015-9348-1

Linsenmeier, R.A. and Saterbak, A. (2020) Fifty years of undergraduate biomedical engineering education.  Ann Biomed Eng. 48 (6): 1590-1615. https://doi.org/10.1007/s10439-020-02494-0

Linsenmeier, R.A. (2020) Required computer science education in BME undergraduate programs. American Society for Engineering Education Conference and Exposition, online conference. https://peer.asee.org/35147

Retina

Dmitriev, A.V., Henderson, D., and Linsenmeier, R.A. (2016) Development of diabetes-induced acidosis in the rat retina. Experimental Eye Research 149:16-25.

Linsenmeier, R.A. and Zhang, H.F. (2017) Retinal Oxygen: From Animals to Humans. Progress in Retinal and Eye Research 58:115-151. PMCID: PMC5441959

Dreffs, A., Henderson, D., Dmitriev, A.V., David A. Antonetti, D.A., and Linsenmeier, R.A. (2018) Retinal pH and acid regulation during metabolic acidosis. Current Eye Research, 43:902-912.

Dmitriev, A.V., Henderson, D. and Linsenmeier, R.A. (2019) Diabetes alters pH control in the rat retina. Invest. Ophthalmol. Visual Sci. 60: 723-730.

Dmitriev, A.V., Dmitriev, A.A., and Linsenmeier, R.A. (2019) The logic of ionic homeostasis: cations are for voltage, but not for volume.  PLOS Computational Biology 15(3): e1006894. https://doi.org/10.1371/journal.pcbi.1006894.

Fawzi, A.A., Fayed, A.E., Linsenmeier, R.A., Gao, J., Yu, F. (2019) Improved macular capillary flow on optical coherence tomography angiography after panretinal photocoagulation for diabetic retinopathy. Am. J. Ophthalmology. 206: 217-227.

Palochak, C.M.A., Lee, H.E., Song, J., Geng, A., Linsenmeier, R.A., Burns, S.A., and Fawzi, A.A. (2019) Retinal Blood Velocity and Flow in Early Diabetes and Diabetic Retinopathy Using Adaptive Optics Scanning Laser Ophthalmoscopy. J. Clinical Medicine, 8: 1165. http://dx.doi.org/10.3390/jcm8081165.

Linsenmeier, R.A. and Troy, J.B (2020) Retinal Bioengineering, in Neural Engineering, 3nd Edition, ed. B. He. New York: Springer

Dmitriev, A.V., Dmitriev, A.A., and Linsenmeier, R.A. (2021) K+-dependent Müller cell-generated components of the electroretinogram. Visual Neuroscience, 38: E010. https://doi.org/10.1017/S0952523821000092

Dmitriev, A.V., Dmitriev, A.A., and Linsenmeier, R.A. (2022) Extracellular K+ reflects light-evoked changes in retinal energy metabolism. Exp. Eye Research, Volume 221, August 2022, 109133. https://doi.org/10.1016/j.exer.2022.109133

Linsenmeier, R.A., Dmitriev, A.V., Dmitriev, A.A. (2023) Oxygen profiles and oxygen consumption in the isolated mouse retina. Exp. Eye Research, Volume 233, 109554. https://doi.org/10.1016/j.exer.2023.109554

Brain

Linsenmeier, R.A., Aksenov, D.P., Faber, H.M., Makar, P. and Wyrwicz, A.M.  (2016) Spontaneous Fluctuations of PO2 in the Rabbit Somatosensory Cortex.  Chapter 39 in Elwell, C.E., Leung, T.S., Harrison, D.K. editors, Oxygen Transport to Tissue XXXVII. Adv Exp Med Biol. 876:311-317.

doi: 10.1007/978-1-4939-3023-4_39

Aksenov, D., Dmitriev, A.V., Miller, M., Linsenmeier, R.A., and Wyrwicz, A.M. (2018) Brain tissue oxygen regulation in awake and anesthetized neonates. Neuropharmacology.  135: 368-375.

Sharma, S.B., Ifergan, I., Linsenmeier, R.A., Xu, D., Cooper, J.G., Miller, S.D. and Kessler, J. (2020) Intravenous immunomodulatory nanoparticle treatment for traumatic brain injury Annals of Neurology, 87(3):442-455

Aksenov, D.P., Doubovikov, E.D., Serdyukova, N.A., Gascoigne, D.A., Linsenmeier, R.A., Drobyshevsky, A. (2022) Brain tissue oxygen dynamics while mimicking the functional deficiency of interneurons. Frontiers in Cellular Neuroscience. 20 October 2022. Sec. Cellular Neurophysiology
https://doi.org/10.3389/fncel.2022.983298

Link to Full List of Publications