Faculty Directory
Ludmilla Aristilde

Associate Professor of Civil and Environmental Engineering, (by courtesy) Chemical and Biological Engineering, and (by courtesy), Earth and Planetary Sciences


2145 Sheridan Road
Tech A316
Evanston, IL 60208-3109

847-491-2999Email Ludmilla Aristilde


Aristilde Research Group


Civil and Environmental Engineering

Chemical and Biological Engineering


NSF Postdoctoral Fellow, Princeton University

Ph.D., Molecular Toxicology, University of California-Berkeley

M.S., Civil and Environmental Engineering, University of California-Berkeley

B.S., Science of Earth Systems, Cornell University

B.F.A., Fine Arts, Cornell University

Research Interests

Dr Aristilde’s areas of expertise are in the combined application of experimental and computational tools in chemistry and biochemistry to gain novel molecular insights underlying the dynamics of organics in environmental processes. The goal of the Aristilde Group is to obtain a fundamental understanding of the “why” and “how” of the environmental behavior of organics, with implications for nutrient cycling, ecosystem health, agricultural productivity, and environmental biotechnology. Her group seeks to figure out the mechanisms responsible for the physical and biological fates. The current research activities of her group are focused on (i) cellular carbon metabolism of organic substrates in environmental bacteria, (ii) catalytic dynamics of nutrient-cycling extracellular enzymes, (iii) the physical chemistry of biomolecules and organic contaminants in environmental matrices, (iv) molecular ecotoxicological targets of organic contaminants.

Selected Publications

  1. Wilkes, R.A.., Waldbauer J., Parker D.J., Zhang L., Guss A.M., Aristilde L. (2023) Complex regulation in a Comamonas platform for diverse aromatic carbon metabolism, Nature Chemical Biology, 19, 651-662.
  2. Solhtalab M., Moller S.R., Gu A.Z., Jaisi L, Aristilde L. (2022). Selectivity in enzymatic phosphorus recycling from biopolymers: Isotope effect, reactivity kinetics, and molecular docking with plant and fungal phosphatases. Environmental Science and Technology, 56, 16441–16452.
  3. Hassanpour B., Blair N., Aristilde L. (2022) Metabolomics of unresolved molecular variability in stream dissolved organic carbon, Water Research, 223, 118923.
  4. Cyle K.T., Klein A.R., Aristilde L., Martinez C.E. (2022) Dynamic utilization of low-molecular-weight organic substrates across a microbial growth rate gradient, Journal of Applied Microbiology, 133, 1479-1495.
  5. Moller S.R., Sakhno Y., Aristilde L., Blake R.E., Jaisi D.P. (2022) Evolution of oxygen isotopologues during enzyme-catalyzed isotope exchange reaction in phosphate and pyrophosphate. ACS Earth and Space Chemistry, 6, 1543–1551.
  6. Pogge von Strandmann P.A.E., Liu X., Liu C.-Y., Wilson D.J., Hammond S.J., Tarbuck G., Aristilde L., Krause A.J., Fraser W.T. (2022) Lithium isotope behaviour during basalt weathering experiments amended with organic acids. Geochimica et Cosmochimica Acta, 328, 37-57.
  7. Park Y., Thongsonboom W., Solhtalab M., Aristilde L. (2022) Strategies of organic phosphorus recycling by soil bacteria: acquisition, metabolism, and regulation, Environmental Microbiology Reports, 14, 3-24.
  8. Li W., Wilkes R.A., Aristilde L. (2022) Effects of phosphonate herbicides on the secretions of plant-beneficial compounds by two plant growth-promoting bacteria: A metabolomics investigation, ACS Environmental Au, 2, 136-149.
  9. Glaser M., Richards B., Steenhius T.S., Aristilde L. (2022) Interactions of phosphonate herbicides with quartz, montmorillonite, and silt-loam agricultural soil, Soil Science Society of America Journal, 86, 209-223.
  10. Wilkes R.A., Waldbauer J., Aristilde L. (2021) Analogous metabolic decoupling in Pseudomonas putida and Comamonas testosteroni implies energetic bypass to facilitate gluconeogeonic growth, mBio, 12, e03259-21.