Faculty Directory
Guillermo A. Ameer

Professor of Biomedical Engineering

Professor of Surgery

Daniel Hale Williams Professor

Director, Center for Advanced Regenerative Engineering


2145 Sheridan Road
Tech B382
Evanston, IL 60208-3107

847-467-2992Email Guillermo Ameer


Ameer Research Lab

Center for Advanced Regenerative Engineering (CARE)


Center for Advanced Regenerative Engineering


Biomedical Engineering


PhD Program in Interdisciplinary Biological Sciences


D.Sc. Chemical Engineering
MIT, Cambridge, MA

B.S Chemical Engineering (Hons)
University of Texas, Austin, TX

Research Interests

On Demand Patient-Specific Medical Devices, Regenerative Engineering, Tissue Engineering, Wound Healing in Diabetes, Monitoring and Controlling the Foreign Body Response, Biomaterials and Cell-Material Interactions, and Targeted Delivery of Therapeutic Molecules, Biomacromolecules, and Cells. 

Significant Recognition

  • Fellow of the American Institute of Medical and Biological Engineering
  • Northwestern University Drew Senyei, MD Translational Research Award, 2006
  • American Heart Association Established Investigator Award, 2006
  • National Science Foundation CAREER Award: Biodegradable elastomeric composite scaffolds for ligament reconstruction, 2006
  • Illinois Institute of Regenerative Medicine: Stem cell-based vascular tissue engineering Award, 2006
  • Wallace H. Coulter Early Career Translational Research Award, 2005

Courses Taught

  • BME344 (Biological Performance of Materials): "Structure-property relationships of materials, physical chemistry of surfaces and interfaces, materials-tissue interactions, applications to the selection and design of materials for medical implants and devices"
  • BME346 (Tissue Engineering): " In vivo molecular, cellular, and organ engineering, with an emphasis on the foundations, techniques, experiments, and clinical applications of tissue engineering"

Selected Publications

  • Jisheng Xiao, Siyu Chen, Ji Yi, Hao F. Zhang, Guillermo A. Ameer, “A Cooperative Copper Metal?Organic Framework-Hydrogel System Improves Wound Healing in Diabetes”, Advanced Functional Materials, (2017)
  • Eun Ji Chung, Matthew J. Sugimoto, Jason L. Koh, Guillermo A. Ameer, “A biodegradable tri-component graft for anterior cruciate ligament reconstruction”, Journal of Tissue Engineering and Regenerative Medicine, (2017)
  • Robert Van Lith, Evan Baker, Henry Ware, Jian Yang, Adam Cyrus Farsheed, Cheng Sun, Guillermo Antonio Ameer, “3D-Printing Strong High-Resolution Antioxidant Bioresorbable Vascular Stents”, Advanced Materials Technologies, (2016)
  • Bin Jiang, Rachel Suen, Jason A. Wertheim, Guillermo A. Ameer, “Targeting Heparin to Collagen within Extracellular Matrix Significantly Reduces Thrombogenicity and Improves Endothelialization of Decellularized Tissues”, Biomacromolecules, (2016)
  • Yunxiao Zhu, Ryan Hoshi, Siyu Chen, Ji Yi, Chongwen Duan, Robert D. Galiano, Hao F. Zhang, Guillermo A. Ameer, “Sustained release of stromal cell derived factor-1 from an antioxidant thermoresponsive hydrogel enhances dermal wound healing in diabetes”, Journal of Controlled Release, (2016)
  • Robert Van Lith, Xuesong Wang, Guillermo Ameer, “Biodegradable Elastomers with Antioxidant and Retinoid-like Properties”, ACS Biomaterial Science and Engineering, (2016)
  • Bin Jiang, Rachel Suen, Jiao Jing Wang, Zheng J. Zhang, Jason A. Wertheim, Guillermo A. Ameer, “Mechanocompatible Polymer-Extracellular-Matrix Composites for Vascular Tissue Engineering”, Advanced healthcare materials, (2016)
  • Bin Jiang, Louisiane Perrin, Dina Kats, Thomas Meade, Guillermo Ameer, “Enabling non-invasive assessment of an engineered endothelium on ePTFE vascular grafts without increasing oxidative stress”, Biomaterials, (2015)
  • Ameer, Guillermo A.; Wertheim, Jason A.; Jiang, Bin; Akgun, Berke; Lam, Ryan C., “A polymer-extracellular matrix composite with improved thromboresistance and recellularization properties”, Acta Biomaterialia, (2015)
  • Yang, Jian; et al.; Hwang, Suk-Won; Lee, Chi Hwan; Cheng, Huanyu, “Biodegradable elastomers and silicon nanomembranes/nanoribbons for stretchable, transient electronics, and biosensors”, Nano Letters, (2015)
  • Ameer, Guillermo A.; Kibbe, Melina R.; Webb, Antonio R.; Gregory, Elaine K.; Vercammen, Janet M., “Periadventitial atRA citrate-based polyester membranes reduce neointimal hyperplasia and restenosis after carotid injury in rats”, American journal of physiology. Heart and circulatory physiology, (2014)
  • Ameer, Guillermo A.; Baler, Kevin; Yang, Jian; Hoshi, Ryan A.; Van Lith, Robert, “A thermoresponsive biodegradable polymer with intrinsic antioxidant properties”, Biomacromolecules, (2014)
  • Ameer, Guillermo A.; Baler, Kevin; Szleifer, Igal; Michael, Raman, “Albumin hydrogels formed by electrostatically triggered self-assembly and their drug delivery capability”, Biomacromolecules, (2014)
  • Ameer, Guillermo A.; Baler, Kevin; Hoshi, Ryan A.; Allen, Josephine B.; Ball, Jordan P., “Advanced nanocomposites for bone regeneration”, Biomaterials Science, (2014)
  • Kibbe, Melina R.; Ameer, Guillermo A.; Yang, Jian; van Lith, Robert; Gregory, Elaine K., “Engineering biodegradable polyester elastomers with antioxidant properties to attenuate oxidative stress in tissues”, Biomaterials, (2014)
  • Szleifer, I.; Baler, K.; Martin, O.A.; Carignano, M.A.; Ameer, G.A., “Electrostatic unfolding and interactions of albumin driven by pH changes: A molecular dynamics study”, Journal of Physical Chemistry B, (2014)
  • Hoshi, Ryan A.; Van Lith, Robert; Jen, Michele C.; Allen, Josephine B.; Lapidos, Karen A., “The blood and vascular cell compatibility of heparin-modified ePTFE vascular grafts”, Biomaterials, (2013)
  • Sharma, Arun K.; Bury, Matthew I.; Fuller, Natalie J.; Marks, Andrew J.; Kollhoff, David M., “Cotransplantation with specific populations of spina bifida bone marrow stem/progenitor cells enhances urinary bladder regeneration”, Proceedings of the National Academy of Sciences of the United States of America, (2013)
  • M. C. Jen, M. C. Serrano, R. van Lith and G. A. Ameer, “Polymer-Based Nitric Oxide Therapies: Recent Insights for Biomedical Applications”, Advanced Functional Materials, (2012)
  • A. K. Sharma, M. I. Bury, N. J. Fuller, D. I. Rozkiewicz, P. V. Hota, D. M. Kollhoff, M. J. Webber, N. Tapaskar, J. W. Meisner, P. J. Lariviere, S. DeStefano, D. Wang, G. A. Ameer and E. Y. Cheng, “Growth factor release from a chemically modified elastomeric poly(1,8-octanediol-co-citrate) thin film promotes angiogenesis in vivo”, Journal of Biomedical Materials Research Part a, (2012)
  • Lapidos, K. A.; Ameer, G. A.; Sprague, S. M., “Impact of serum source and inflammatory cytokines on the isolation of endothelial colony-forming cells from peripheral blood”, Journal of Tissue Engineering and Regenerative Medicine, (2012)
  • E. J. Chung, M. Sugimoto, J. L. Koh and G. A. Ameer, “Low-pressure foaming: a novel method for the fabrication of porous scaffolds for tissue engineering”, Tissue engineering. Part C, Methods, (2012)
  • G Ameer, J Yang, A Webb, “Novel biodegradable elastomeric scaffold for tissue engineering and light scattering fingerprinting methods for testing the same”, US Patent App. 12/370,312, (2009)
  • GA Ameer, Y Zhang, “Method for Removal or Inactivation of Heparin”, US Patent App. 12/505,985, (2009)


  • Transdermal Thermal Polymerization (U.S. patent #7,097,855 issued 08-2006) G.A. Ameer, E.T. Crumpler, and R. Langer
  • Multidimensional Elastic Light Scattering (Application #11/261,452) V. Backman, H. Roy, R. Wali, Y. Kim , Y. Liu, J. Yang , J. Allen, A. Webb, and G.A. Ameer.
  • Apparatus for Treating Whole Blood (U.S. Patent #6099730 issued 08-2000) G. A. Ameer , R. Langer, M. Rupnik, H. Ploegh, and E. Grovender.
  • Cell Delivery Using Controllable Degradable Mesh-Gel Constructs (U.S. Patent #6699470 issued 03-2004) G. A. Ameer and R. Langer.
  • Biodegradable Polymer (Application # 601340432, US and International, pending) Y. Wang, G. A. Ameer, and R. Langer
  • Biodegradable Elastomers for Tissue Engineering (Pending) J. Yang, A. Webb, and G.A. Ameer.
  • Functionalizing Medical Implants: A Tissue Engineering Approach (Pending) J. Yang and G.A. Ameer.
  • A Novel(diol-co-citrate) Hydroxyapatite Composite for Clinical Fixation Devices (Pending) ,J. Yang, H. Qiu, and G.A. Ameer.
  • Receptor-Based Blood Detoxification System (Pending) C. Daniels, S. Sprague, and G.A. Ameer.