Faculty Directory
Jason A. Wertheim

Edward G. Elcock Professor

Vice Chair for Research, Department of Surgery

Associate Professor of Surgery (Organ Transplantation Division)

Associate Professor of Biomedical Engineering


NMH/Arkes Family Pavilion Suite 1900
676 N Saint Clair
Chicago, IL 60611

312-695-8900Email Jason A. Wertheim


Chemistry of Life Processes Institute

Comprehensive Transplant Center


Biomedical Engineering


BS: Massachussetts Institute of Technology, Chemical Engineering (1996)

MD: University of Pennsylvania (2004)

PhD: University of Pennsylvania, Bioengineering (2002)

Fellowship: University of California, Los Angeles, Transplantation (2011)

Residency: Massachusetts General Hospital, Surgery (2009)

Research Interests

Dr. Jason Wertheim is a transplant surgeon and biomedical engineer whose research focuses on discovering new methods to develop liver and kidney tissue in the laboratory to alleviate the problem of organ shortage. His research involves a multidisciplinary, tissue engineering and regenerative medicine approach to develop organ scaffolds using pluripotent stem/progenitor cells that support the growth of new tissues that will eventually become whole organs.

Selected Publications

Mechanocompatible Polymer-Extracellular-Matrix Composites for Vascular Tissue Engineering.
Jiang B, Suen R, Wang JJ, Zhang ZJ, Wertheim JA, Ameer GA.
Adv Healthc Mater. 2016 Apr 24. doi: 10.1002/adhm.201501003. [Epub ahead of print]
PMID: 27109033

Challenging Regeneration to Transform Medicine.
Tsukamoto A, Abbot SE, Kadyk LC, DeWitt ND, Schaffer DV, Wertheim JA, Whittlesey KJ, Werner MJ.
Stem Cells Transl Med. 2016 Jan;5(1):1-7. doi: 10.5966/sctm.2015-0180. Epub 2015 Nov 25. Review.
PMID: 26607174

SIRT1 Overexpression Maintains Cell Phenotype and Function of Endothelial Cells Derived from Induced Pluripotent Stem Cells.
Jiang B, Jen M, Perrin L, Wertheim JA, Ameer GA.
Stem Cells Dev. 2015 Dec 1;24(23):2740-5. doi: 10.1089/scd.2015.0191. Epub 2015 Oct 28.
PMCID: PMC4653826

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development.
Uzarski JS, Su J, Xie Y, Zhang ZJ, Ward HH, Wandinger-Ness A, Miller WM, Wertheim JA.
J Vis Exp. 2015 Aug 10;(102):e53271. doi: 10.3791/53271.
PMCID: PMC4593606

View all publications

Selected Books and Book Chapters

Wertheim J, Benedetto W. ICU Care Following Liver, Kidney, and Lung Transplantation. In: Bigatello LM, editor. 2010. The Critical Care Handbook of the Massachusetts General Hospital, 5th Edition. Philadelphia: Lippincott Williams & Wilkins

Wertheim JA. Alcoholic Liver Disease. In: Gordon S, Holt C, Kaufman S, editors. 2009. The Dumont-UCLA Transplant Guide 3rd Edition. Los Angeles: Regents of the University of California