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  • Nov
    12

    Appl Math: Mariela Petkova on "Carving Circuits from Correlative Connectomics"

    McCormick-Engineering Sciences and Applied Mathematics (ESAM)

    11:15 AM M416, Technological Institute

    EVENT DETAILS

    Title: Carving Circuits from Correlative Connectomics

    Speaker: Mariela Petkova, Harvard University

    Abstract: Tracing the wiring diagram of a neural circuit is a powerful approach to test
    computational models of brain function. Connectomics – the mapping of
    neurons and their connections in the brain – poses formidable technical and
    conceptual challenges. The former entails the acquisition and reduction of
    vast amounts of electron microscopy image data to connectivity matrices,
    achieved through multi-year, multi-team collaborative efforts. The latter
    challenge is the problem of coarse-graining the connectivity matrices to
    neural circuits which exhibit neural activity and function. I will describe both
    challenges in the context of mapping the nervous system of a small
    vertebrate – the larval zebrafish. In the same animal, we pair electron
    microscopy with functional information from light microscopy to interrogate
    neural circuit models for animal behavior from sensory inputs to motor output.

    Zoom: https://northwestern.zoom.us/j/94241764594

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    TIME Tuesday, November 12, 2024 at 11:15 AM - 12:15 PM

    LOCATION M416, Technological Institute    map it

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    CONTACT Ted Shaeffer    ted.shaeffer@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics (ESAM)