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  • Jan
    31

    Richard Braun: Semi-automated Tear Breakup Detection and Modeling on the Ocular Surface

    McCormick-Engineering Sciences and Applied Mathematics (ESAM)

    11:15 AM M416, Technological Institute

    EVENT DETAILS

    Title: Semi-automated Tear Breakup Detection and Modeling on the Ocular Surface

    Speaker: : Richard Braun, Carl J. Rees Professor, Department of Mathematical Sciences, University of Delaware

    Abstract: The tear film is a thin fluid multilayer left on the eye surface after a blink. A good tear film is essential for health and proper function of the eye. Millions of people have a condition called dry eye disease (DED) that is thought to be closely linked to the tear film. DED inhibits vision and may lead to inflammation and ocular surface damage. However, there is little quantitative data about tear film failure, often called tear break up (TBU). Currently, it is not possible to directly measure important variables such as tear osmolarity (saltiness) within areas of TBU. We present a mostly automatic method that we have developed to extract data from video of the tear film dyed with fluorescein (for visualization). We have extracted data for 15 healthy subjects resulting in 467 instances of TBU. Using parameter identification from fits to appropriate math models, we estimate which mechanisms are most important in each instance and determine critical variables such as osmolarity within regions of TBU. Not only is new data obtained, but far more data, enabling statistical methods to be applied. So far, the methods provide baseline data for TBU in healthy subjects. Future work will produce data from DED subjects.

    **Please note, this event will be held in-person, as well as online via Zoom at the following link: https://northwestern.zoom.us/j/98201248117

    Special Note: This colloquium is on Tuesday at 11:15am, the new regular time for the applied math colloquium.

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    TIME Tuesday, January 31, 2023 at 11:15 AM - 12:15 PM

    LOCATION M416, Technological Institute    map it

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    CONTACT Ted Shaeffer    ted.shaeffer@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics (ESAM)

  • Feb
    4

    Science, Art, and the Search for Meaning: Exhibition Opening Conversation with Dario Robleto

    Block Museum of Art

    2:00 PM McCormick Auditorium, Norris University Center

    EVENT DETAILSmore info

    TIME Saturday, February 4, 2023 at 2:00 PM - 3:30 PM

    LOCATION McCormick Auditorium, Norris University Center    map it

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    CONTACT Block Museum of Art    block-museum@northwestern.edu EMAIL

    CALENDAR Block Museum of Art

  • Mar
    11

    Winter Classes End

    University Academic Calendar

    All Day

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    TIME Saturday, March 11, 2023

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Mar
    18

    Spring Break Begins

    University Academic Calendar

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    TIME Saturday, March 18, 2023

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Mar
    24

    Winter Degrees Conferred

    University Academic Calendar

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    TIME Friday, March 24, 2023

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

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  • Mar
    27

    Spring Break Ends

    University Academic Calendar

    All Day

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    TIME Monday, March 27, 2023

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar