News & EventsDepartment Events
Events
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Jan31
EVENT DETAILS
Title: Semi-automated Tear Breakup Detection and Modeling on the Ocular Surface
Speaker: : Richard Braun, Carl J. Rees Professor, Department of Mathematical Sciences, University of Delaware
Abstract: The tear film is a thin fluid multilayer left on the eye surface after a blink. A good tear film is essential for health and proper function of the eye. Millions of people have a condition called dry eye disease (DED) that is thought to be closely linked to the tear film. DED inhibits vision and may lead to inflammation and ocular surface damage. However, there is little quantitative data about tear film failure, often called tear break up (TBU). Currently, it is not possible to directly measure important variables such as tear osmolarity (saltiness) within areas of TBU. We present a mostly automatic method that we have developed to extract data from video of the tear film dyed with fluorescein (for visualization). We have extracted data for 15 healthy subjects resulting in 467 instances of TBU. Using parameter identification from fits to appropriate math models, we estimate which mechanisms are most important in each instance and determine critical variables such as osmolarity within regions of TBU. Not only is new data obtained, but far more data, enabling statistical methods to be applied. So far, the methods provide baseline data for TBU in healthy subjects. Future work will produce data from DED subjects.
**Please note, this event will be held in-person, as well as online via Zoom at the following link: https://northwestern.zoom.us/j/98201248117
Special Note: This colloquium is on Tuesday at 11:15am, the new regular time for the applied math colloquium.
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TIME Tuesday, January 31, 2023 at 11:15 AM - 12:15 PM
LOCATION M416, Technological Institute map it
CONTACT Ted Shaeffer ted.shaeffer@northwestern.edu EMAIL
CALENDAR McCormick-Engineering Sciences and Applied Mathematics (ESAM)
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Mar11
EVENT DETAILS
Winter Classes End
TIME Saturday, March 11, 2023
CONTACT Office of the Registrar nu-registrar@northwestern.edu EMAIL
CALENDAR University Academic Calendar
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Mar18
EVENT DETAILS
Spring Break Begins
TIME Saturday, March 18, 2023
CONTACT Office of the Registrar nu-registrar@northwestern.edu EMAIL
CALENDAR University Academic Calendar
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Mar24
EVENT DETAILS
Winter Degrees Conferred
TIME Friday, March 24, 2023
CONTACT Office of the Registrar nu-registrar@northwestern.edu EMAIL
CALENDAR University Academic Calendar
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Mar27
EVENT DETAILS
Spring Break Ends
TIME Monday, March 27, 2023
CONTACT Office of the Registrar nu-registrar@northwestern.edu EMAIL
CALENDAR University Academic Calendar