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  • Oct
    19

    Jessica Conway: HIV Viral Rebound Heterogeneity Following Treatment Interruption

    McCormick-Engineering Sciences and Applied Mathematics

    4:00 PM

    EVENT DETAILS

    Title: HIV Viral Rebound Heterogeneity Following Treatment Interruption

    Speaker: Jessica Conway, PhD, Penn State University

    Special Note: To attend this zoom-talk, please register using the following link: https://northwestern.zoom.us/meeting/register/tJMpfuCoqDwjGtQ2nJ00QhB9SmOAWO7m43Qq. Upon registering, you will receive an email containing information about joining the meeting. When clicking at the link please make sure it is not split into two lines.

    Abstract: Antiretroviral therapy (ART) effectively controls HIV infection, suppressing HIV viral loads to levels undetectable using commercial testing. Typically, suspension of therapy is rapidly followed by rebound of viral loads to high, pre-therapy levels. However recent observations give nuance to that statement: in a small fraction of cases, rebound may be delayed by months, years, or even possibly, permanently. We will discuss a proposed phenomenological model assuming simple heterogeneous dynamics in latent reservoir activation, which we assume is the source of viral rebound, to make predictions on time to rebound post-treatment suspension. In particular, we rely on time-inhomogeneous branching processes to derive a mechanistically-motivated survival function for time-to-rebound. We validate our model with data from Li et al. (2016), specifically a collection of observations of times to viral rebound across 235 study participants following treatment suspension. We show that our model provides good agreement with survival curves generated from study participants. Finally if there's time we will discuss hypotheses for biology underlying the phenomenological model and aimed at generating testable predictions on achieving durable infection control following interruption of ART.

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    TIME Monday, October 19, 2020 at 4:00 PM - 5:00 PM

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    CONTACT Madeline Kennedy    madeline.kennedy@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics

  • Apr
    23

    Appl Math: Tom Dean on "Contrail Climate Impacts: Modeling and Mitigation Strategies"

    McCormick-Engineering Sciences and Applied Mathematics (ESAM)

    11:15 AM M416, Technological Institute

    EVENT DETAILS

    TIME Tuesday, April 23, 2024 at 11:15 AM - 12:15 PM

    LOCATION M416, Technological Institute    map it

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    CONTACT Ted Shaeffer    ted.shaeffer@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics (ESAM)

  • Apr
    30

    Appl Math: Ehud Yariv on "Shocks and Caps in Drop Electrohydrodynamics"

    McCormick-Engineering Sciences and Applied Mathematics (ESAM)

    11:15 AM M416, Technological Institute

    EVENT DETAILS

    TIME Tuesday, April 30, 2024 at 11:15 AM - 12:15 PM

    LOCATION M416, Technological Institute    map it

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    CONTACT Ted Shaeffer    ted.shaeffer@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics (ESAM)

  • May
    7

    Appl Math: Pankaj Mehta on "Mathematics of Life Seminar Series: Randomness, Complexity, and the Biological Frontier"

    McCormick-Engineering Sciences and Applied Mathematics (ESAM)

    11:15 AM M416, Technological Institute

    EVENT DETAILS

    TIME Tuesday, May 7, 2024 at 11:15 AM - 12:15 PM

    LOCATION M416, Technological Institute    map it

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    CONTACT Ted Shaeffer    ted.shaeffer@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics (ESAM)

  • May
    8

    Extending Care: A Conversation about Conservation and Futurity

    Block Museum of Art

    6:00 PM Block Museum of Art, Mary and Leigh

    EVENT DETAILSmore info

    TIME Wednesday, May 8, 2024 at 6:00 PM - 7:30 PM

    LOCATION Block Museum of Art, Mary and Leigh    map it

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    CONTACT Block Museum of Art    block-museum@northwestern.edu EMAIL

    CALENDAR Block Museum of Art

  • May
    14

    Appl Math: Rony Granek on "Active Fractal Networks with Stochastic Force Monopoles and Force Dipoles Unravel Subdiffusion of Chromosomal Loci"

    McCormick-Engineering Sciences and Applied Mathematics (ESAM)

    11:15 AM M416, Technological Institute

    EVENT DETAILS

    TIME Tuesday, May 14, 2024 at 11:15 AM - 12:15 PM

    LOCATION M416, Technological Institute    map it

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    CONTACT Ted Shaeffer    ted.shaeffer@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics (ESAM)

  • May
    21

    Appl Math: Andrew Stuart on "Title TBA"

    McCormick-Engineering Sciences and Applied Mathematics (ESAM)

    11:15 AM M416, Technological Institute

    EVENT DETAILS

    TIME Tuesday, May 21, 2024 at 11:15 AM - 12:15 PM

    LOCATION M416, Technological Institute    map it

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    CONTACT Ted Shaeffer    ted.shaeffer@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics (ESAM)

  • May
    28

    Appl Math: Pascale Garaud on "Title TBA"

    McCormick-Engineering Sciences and Applied Mathematics (ESAM)

    11:15 AM M416, Technological Institute

    EVENT DETAILS

    TIME Tuesday, May 28, 2024 at 11:15 AM - 12:15 PM

    LOCATION M416, Technological Institute    map it

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    CONTACT Ted Shaeffer    ted.shaeffer@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics (ESAM)

  • Jun
    10

    Northwestern Engineering PhD Hooding and Master's Degree Recognition Ceremony

    McCormick School of Engineering and Applied Science

    9:00 AM Welsh-Ryan Arena

    EVENT DETAILSmore info

    TIME Monday, June 10, 2024 at 9:00 AM - 11:00 AM

    LOCATION Welsh-Ryan Arena   

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    CONTACT Amy Pokrass    amy.pokrass@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Jun
    10

    Northwestern Engineering Undergraduate Convocation

    McCormick School of Engineering and Applied Science

    2:00 PM Welsh-Ryan Arena

    EVENT DETAILSmore info

    TIME Monday, June 10, 2024 at 2:00 PM - 4:00 PM

    LOCATION Welsh-Ryan Arena   

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    CONTACT Amy Pokrass    amy.pokrass@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science