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  • Oct
    19

    Jessica Conway: HIV Viral Rebound Heterogeneity Following Treatment Interruption

    McCormick-Engineering Sciences and Applied Mathematics

    4:00 PM

    EVENT DETAILS

    Title: HIV Viral Rebound Heterogeneity Following Treatment Interruption

    Speaker: Jessica Conway, PhD, Penn State University

    Special Note: To attend this zoom-talk, please register using the following link: https://northwestern.zoom.us/meeting/register/tJMpfuCoqDwjGtQ2nJ00QhB9SmOAWO7m43Qq. Upon registering, you will receive an email containing information about joining the meeting. When clicking at the link please make sure it is not split into two lines.

    Abstract: Antiretroviral therapy (ART) effectively controls HIV infection, suppressing HIV viral loads to levels undetectable using commercial testing. Typically, suspension of therapy is rapidly followed by rebound of viral loads to high, pre-therapy levels. However recent observations give nuance to that statement: in a small fraction of cases, rebound may be delayed by months, years, or even possibly, permanently. We will discuss a proposed phenomenological model assuming simple heterogeneous dynamics in latent reservoir activation, which we assume is the source of viral rebound, to make predictions on time to rebound post-treatment suspension. In particular, we rely on time-inhomogeneous branching processes to derive a mechanistically-motivated survival function for time-to-rebound. We validate our model with data from Li et al. (2016), specifically a collection of observations of times to viral rebound across 235 study participants following treatment suspension. We show that our model provides good agreement with survival curves generated from study participants. Finally if there's time we will discuss hypotheses for biology underlying the phenomenological model and aimed at generating testable predictions on achieving durable infection control following interruption of ART.

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    TIME Monday, October 19, 2020 at 4:00 PM - 5:00 PM

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    CONTACT Madeline Kennedy    madeline.kennedy@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics

  • Nov
    2

    Zachary Kilpatrick: Heterogeneity Improves Speed and Accuracy in Social Networks

    McCormick-Engineering Sciences and Applied Mathematics

    4:00 PM

    EVENT DETAILS

    TIME Monday, November 2, 2020 at 4:00 PM - 5:00 PM

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    CONTACT Madeline Kennedy    madeline.kennedy@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics

  • Nov
    6

    Last day to drop a class for Fall in CAESAR. Any requests after this date result in a W on the transcript and must go through the course withdrawal process.

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Friday, November 6, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Nov
    11

    One McCormick: GradSWE and Women in Science and Engineering Research (WISER)

    McCormick School of Engineering and Applied Science

    12:00 PM

    EVENT DETAILS

    TIME Wednesday, November 11, 2020 at 12:00 PM - 12:30 PM

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    CONTACT Northwestern Engineering Events    northwestern-engineering-events@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Nov
    13

    Dean's Seminar Series: Dirk Brockmann

    McCormick School of Engineering and Applied Science

    11:00 AM

    EVENT DETAILS

    TIME Friday, November 13, 2020 at 11:00 AM - 12:00 PM

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    CONTACT Northwestern Engineering Events    mccormick-events@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Nov
    19

    Pre-registration for Winter Quarter begins, ending on November 20.

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    EVENT DETAILS

    TIME Thursday, November 19, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

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  • Nov
    23

    Undergraduate registration for Winter 2021 begins

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    TIME Monday, November 23, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

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  • Nov
    24

    Last Day for Face-to-Face Instruction

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    EVENT DETAILS

    TIME Tuesday, November 24, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Nov
    25

    Thanksgiving vacation begins

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    TIME Wednesday, November 25, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

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  • Dec
    2

    Fall examinations begin (all remote)

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    TIME Wednesday, December 2, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Dec
    8

    Fall examinations end

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    EVENT DETAILS

    TIME Tuesday, December 8, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

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  • Dec
    18

    Fall Degrees Conferred

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    TIME Friday, December 18, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

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  • Dec
    28

    Winter Recess - University Closed

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    TIME Monday, December 28, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

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  • Dec
    29

    Winter Recess - University Closed

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    TIME Tuesday, December 29, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

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