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  • Jan
    27

    Jörn Dunkel: Symmetry Breaking and Pattern Formation in Soft Matter and Active Fluids

    McCormick-Engineering Sciences and Applied Mathematics

    4:00 PM M416, Technological Institute

    EVENT DETAILS

    Title: Symmetry Breaking and Pattern Formation in Soft Matter and Active Fluids

    Speaker: Jorn Dunkel, PhD, Massachusetts Institue of Technology

    Abstract: The brain contains a diverse array of cells with dramatically different shapes, activity patterns, and molecular composition. The advent of single-cell RNA-sequencing, which quantifies the gene expression-based molecular makeup of individual cells, has resulted in brain-specific data sets with measurements for thousands of features in each cell. Two fundamental mathematical questions arise from this type of large-scale data: 1) a clustering problem, with the goal of grouping cells together in the molecular state space to identify stable cell type profiles, and 2) a combinatorial optimization problem, with the goal of identifying putative locations in state space that are likely to be stable, but have not been observed yet. The clustering problem is well-formulated and studied, and can be solved with a number of matrix decomposition methods under reasonable assumptions. The second question – that of predicting the existence of stable profiles that have not been observed directly – is degenerate from a strictly dynamical systems point of view, but can be formulated as a combinatorial optimization problem, yielding experimentally testable predictions. Ultimately, applying these methods to these data sets leads to new insight into diverse array of components that make up the brain.

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    TIME Monday, January 27, 2020 at 4:00 PM - 5:00 PM

    LOCATION M416, Technological Institute    map it

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    CONTACT Kendall Minta    kendall.minta@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics

  • Jan
    20

    Suspension of classes for observance of Martin Luther King Jr. Day

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Monday, January 20, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Mar
    21

    Spring Break Begins

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Saturday, March 21, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Mar
    31

    Spring Classes Begin 8 a.m. - Note: Northwestern Monday - Monday classes

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Tuesday, March 31, 2020

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar