Faculty Directory
Arthur Prindle

Associate Professor of Chemical and Biological Engineering and (by courtesy) Biomedical Engineering

Associate Professor of Biochemistry and Molecular Genetics

Contact

2145 Sheridan Road
Tech
Evanston, IL 60208-3109

312-503-4344Email Arthur Prindle

Website

Prindle Lab

Departments

Chemical and Biological Engineering

Education

Ph.D., Bioengineering, University of California, San Diego, CA

B.S., Chemical Engineering, with honors, California Institute of Technology, Pasadena, CA


Research Interests

We are interested in understanding how molecular and cellular interactions give rise to collective behaviors in microbial communities. We use synthetic biology, quantitative microscopy, and microfluidics to directly investigate the molecular mechanisms behind how cells communicate across broad spatial and temporal scales. Our goal is to apply these principles to develop new synthetic biology approaches to biomedical problems through microbiome engineering.


Selected Publications

  • Quillin, Sarah J.; Luo, Di; Gavagan, Aoife; Prindle, Arthur; Seifert, H. Steven, A droplet digital PCR assay to measure pilin antigenic variation frequency in Neisseria gonorrhoeae, mSphere (2025).
  • Lander, Stephen M.; Fisher, Garth; Everett, Blake A.; Tran, Peter; Prindle, Arthur, Correction to, npj Biofilms and Microbiomes (2024).
  • Kennelly, Corey; Prindle, Arthur, Substrate identification of putative NCS1 and NCS2 nucleobase transporters in Pseudomonas aeruginosa, mBio (2024).
  • Karim, Ashty Stephen; Brown, Dylan M.; Archuleta, Chloé M.; Grannan, Sharisse; Aristilde, Ludmilla; Goyal, Yogesh; Leonard, Joshua N; Mangan, Niall M.; Prindle, Arthur; Rocklin, Gabriel J.; Tyo, Keith J.; Zoloth, Laurie S; Jewett, Michael Christopher; Calkins, Susanna C; Kamat, Neha P.; Tullman-Ercek, Danielle; Lucks, Julius B., Deconstructing synthetic biology across scales, Nature communications (2024).
  • Lander, Stephen M.; Fisher, Garth; Everett, Blake A.; Tran, Peter; Prindle, Arthur, Secreted nucleases reclaim extracellular DNA during biofilm development, npj Biofilms and Microbiomes (2024).
  • Kennelly, Corey; Tran, Peter; Prindle, Arthur, Environmental purines decrease Pseudomonas aeruginosa biofilm formation by disrupting c-di-GMP metabolism, Cell reports (2024).
  • Tran, Peter; Lander, Stephen M.; Prindle, Arthur, Active pH regulation facilitates Bacillus subtilis biofilm development in a minimally buffered environment, mBio (2024).
  • Everett, Blake A.; Tran, Peter; Prindle, Arthur, Toward manipulating serotonin signaling via the microbiota–gut–brain axis, Current Opinion in Biotechnology (2022).