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  • Apr
    30

    EES Seminar: Jinglin Hu

    McCormick - Civil and Environmental Engineering

    2:00 PM

    EVENT DETAILS

    Towards Understanding Microbial Degradation of Veterinary Drugs in Large Saltwater Aquariums

    Abstract

    In order to address the disappearance of chloroquine phosphate, an anti-parasitic drug, and to restore drug efficacy in aquarium systems, we collaborated with Shedd Aquarium and conducted microbial and chemical investigations focusing on tropical saltwater systems. Chloroquine phosphate is widely used as a bath pharmaceutical to treat external protozoa infections caused by Cryptocaryon irritans in aquariums, including large public aquariums like Shedd. Although common, this parasitic infection can be harmful or even deadly to animals that are already under stress from activities such as long-distance transport. For full parasite removal, a bath treatment is expected to last 14 to 21 days, during which time the chloroquine concentration needs to be maintained above a therapeutic dose. From November 2018 to January 2020, several exhibitions and quarantine systems treated with chloroquine experienced severe chloroquine degradation and the therapeutic dose could not be maintained for the prescribed period. Immediate water change but did not yield any improvement. As a result, the effectiveness of the drug has been severely jeopardized, making the animals vulnerable to ongoing infections as well as possible Cryptocaryon irritans outbreaks in the future.

    In our investigation, we focused on two tropical saltwater systems. Our findings show that aquarium microbiome composition is impacted by the aquarium's residents, sampling location (tank vs pipeline), and chloroquine dosing. Several taxa belonging to the phyla Actinobacteria, Bacteroidetes, Chloroflexi, and Proteobacteria, along with functional genes related to pathways such as phenylethylamine degradation and denitrification, were found to be differentially abundant between samples where chloroquine degradation was observed and those without degradation. Overall, we found that the degradation was biological and associated with biofilm attached to water pipes. Together, these results provide practical mitigation options to prevent or delay the development of microbial chloroquine degradation. Our results further demonstrate the need to improve our understanding of the aquarium microbiome to best support healthy animal populations in closed loop aquarium systems.

    Bio

    Jinglin Hu is a fifth year PhD student in the Hartmann Group in the Department of Civil and Environmental Engineering at Northwestern University. Her research focuses on understanding the response of bacterial communities to chemical perturbation in the environments. She graduated from the University of Minnesota, Twin Cities with a B.S. in Environmental and Ecological Engineering in 2016.

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    TIME Friday, April 30, 2021 at 2:00 PM - 3:00 PM

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    CONTACT Tierney Acott    tierney.acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • May
    13

    TAM Seminar: Dr. Nathalie Vriend

    McCormick - Civil and Environmental Engineering

    10:00 AM

    EVENT DETAILSmore info

    TIME Thursday, May 13, 2021 at 10:00 AM - 11:00 AM

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    CONTACT Alison Rodriguez    alison.rodriguez@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • May
    14

    Social Equity & Racial Justice Seminar: Lee Bey

    McCormick - Civil and Environmental Engineering

    2:00 PM

    EVENT DETAILS

    TIME Friday, May 14, 2021 at 2:00 PM - 3:00 PM

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    CONTACT Tierney Acott    tierney.acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • May
    19

    Osterberg Lecture: Edward Kavazanjian, Jr.

    McCormick - Civil and Environmental Engineering

    11:00 AM

    EVENT DETAILS

    TIME Wednesday, May 19, 2021 at 11:00 AM - 12:30 PM

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    CONTACT Alison Rodriguez    alison.rodriguez@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • May
    20

    Julio M. Ottino: Prediction, Understanding, and the Unreasonable Effectiveness of Mathematics: A View Through the Window of Mixing

    McCormick-Engineering Sciences and Applied Mathematics

    12:00 PM

    EVENT DETAILS

    TIME Thursday, May 20, 2021 at 12:00 PM - 1:00 PM

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    CONTACT Madeline Kennedy    madeline.kennedy@northwestern.edu EMAIL

    CALENDAR McCormick-Engineering Sciences and Applied Mathematics

  • May
    21

    EES Seminar: Edward Kolodziej

    McCormick - Civil and Environmental Engineering

    2:00 PM

    EVENT DETAILS

    TIME Friday, May 21, 2021 at 2:00 PM - 3:00 PM

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    CONTACT Tierney Acott    tierney.acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • May
    28

    EES Seminar: Nadine Borduas-Dedekind

    McCormick - Civil and Environmental Engineering

    2:00 PM

    EVENT DETAILS

    TIME Friday, May 28, 2021 at 2:00 PM - 3:00 PM

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    CONTACT Tierney Acott    tierney.acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • May
    31

    Memorial Day (no classes)

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Monday, May 31, 2021

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Jun
    5

    Spring classes end

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Saturday, June 5, 2021

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Jun
    7

    Spring examinations begin

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Monday, June 7, 2021

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Jun
    12

    Spring examinations end

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Saturday, June 12, 2021

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Jun
    13

    McCormick School of Engineering Convocation (Tentative)

    McCormick School of Engineering and Applied Science

    1:00 PM Ryan Field

    EVENT DETAILSmore info

    TIME Sunday, June 13, 2021 at 1:00 PM - 3:00 PM

    LOCATION Ryan Field    map it

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    CONTACT Northwestern Engineering Events    northwestern-engineering-events@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Jun
    14

    Commencement (Tentative)

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Monday, June 14, 2021

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Jun
    18

    Spring Degrees Conferred

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Friday, June 18, 2021

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar