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Mar
4
TAM Seminar: Prof. Wendy C. Crone
McCormick - Civil and Environmental Engineering
10:00 AM
EVENT DETAILSmore info
TAM Seminar Series Presents:
Wendy C. Crone
Karen Thompson Medhi Professor of the College of Engineering
Discovery Fellow in the Wisconsin Institute for Discovery
University of Wisconsin-Madison
An Engineered Culture System for Human Cardiac Syncytium: Structural, Mechanical, and Electrical Readouts of Heart Cells in a Dish
Thursday, March 4th • 10:00AM CST
Please log on with your Northwestern account (https://northwestern.zoom.us) to join.
Abstract
Human pluripotent stem cell–derived cardiomyocytes (hPSC-CMs) have emerged as an exciting new tool for cardiac research and can serve as a pre-clinical platform for drug development and disease modeling studies. However, these aspirations are limited by current culture methods in which hPSC-CMs resemble fetal human cardiomyocytes in terms of structure and function. The Crone Lab has produced a novel platform for use with hPSC-CMs and human pluripotent stem cell-derived cardiac fibroblasts (hPSC-CFs), that includes patterned extracellular matrix (ECM) with physiological substrate stiffness to enhance these cells for in vitro studies. The platform is amenable to structural, mechanical, and electrical characterization.
When iPSC-CFs are confined to the micropatterned features of the platform they remodel the ECM into anisotropic fibers. Micropatterned lanes promote the cellular and myofibril alignment of hPSC-CMs while the addition of micropatterned bridges enable formation of a functional cardiac syncytium that beats synchronously over a large 2D area within the platform. Investigation of electrophysiological properties of the patterned cardiac constructs with optical mapping shows that they have anisotropic electrical impulse propagation, as occurs in the native myocardium. Interrogation of the mechanical function of the pattern constructs using digital image correlation (DIC) demonstrates the utility of this platform for mechanical characterization of coordinated contractions. Our results also show that iPSC-CFs influence iPSC-CM function with accelerated Ca2+ transient rise-up time and greater contractile strains in the co-culture conditions compared to when iPSC-CMs are cultured alone. Preliminary results will also be presented on the utility of this platform to investigate a hypertrophic cardiomyopathy (HCM) disease model.
Biography
Wendy C. Crone is the Karen Thompson Medhi Professor in the Department of Engineering Physics at the University of Wisconsin–Madison and is a Discovery Fellow with the Wisconsin Institute for Discovery. Her research is in the area of solid mechanics and is connected with biotechnology and nanotechnology. She has applied her technical expertise to improving fundamental understanding of mechanical response of materials, enhancing material behavior through surface modification and nanostructuring, exploring the interplay between cells and the mechanics of their surroundings, and developing new material applications and medical devices. Prof. Crone is a Fellow of the Society for Experimental Mechanics and has served in several leadership roles at UW-Madison, including prior appointments as Interim Dean and Associate Dean of the Graduate School.
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TIME Thursday, March 4, 2021 at 10:00 AM - 11:00 AM
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CONTACT Alison Rodriguez    alison.rodriguez@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering
Sep
8
Welcome & Breakfast for New McCormick PhD Students
McCormick School of Engineering and Applied Science
9:00 AM LR2 & Tech East Plaza, Technological Institute
EVENT DETAILS
Enjoy a welcome from Dean Christopher A. Schuh and other McCormick leaders, and receive a Northwestern Engineering T-shirt. A free light breakfast on the Tech East Plaza will follow.
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TIME Monday, September 8, 2025 at 9:00 AM - 10:00 AM
LOCATION LR2 & Tech East Plaza, Technological Institute    map it
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CONTACT Andi Joppie    andi.joppie@northwestern.edu EMAIL
CALENDAR McCormick School of Engineering and Applied Science
Sep
10
CEE Department BBQ
McCormick - Civil and Environmental Engineering (CEE)
4:00 PM Dawes House
EVENT DETAILS
TBA
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TIME Wednesday, September 10, 2025 at 4:00 PM - 7:00 PM
LOCATION Dawes House   
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Sep
12
New Undergraduate Fall 2025 Registration
University Academic Calendar
All Day
EVENT DETAILS
New Undergraduate Fall 2025 Registration
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TIME Friday, September 12, 2025
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CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL
CALENDAR University Academic Calendar
Sep
12
New Graduate Student Orientation
McCormick - Civil and Environmental Engineering (CEE)
9:00 AM M345, Technological Institute
EVENT DETAILS
TBA
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TIME Friday, September 12, 2025 at 9:00 AM - 5:00 PM
LOCATION M345, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Sep
15
Welcome & Luncheon for New Full-time Graduate Students
McCormick School of Engineering and Applied Science
11:00 AM Ryan Auditorium & Tech East Plaza, Technological Institute
EVENT DETAILS
Enjoy a welcome from Dean Christopher A. Schuh and other McCormick leaders, and receive a Northwestern Engineering T-shirt. A free lunch on the Tech East Plaza will follow.
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TIME Monday, September 15, 2025 at 11:00 AM - 12:30 PM
LOCATION Ryan Auditorium & Tech East Plaza, Technological Institute    map it
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CONTACT Andi Joppie    andi.joppie@northwestern.edu EMAIL
CALENDAR McCormick School of Engineering and Applied Science
Sep
16
Fall Classes Begin. Change of Registration (Drop/Add) Late registration for returning students begins
University Academic Calendar
All Day
EVENT DETAILS
Fall Classes Begin. Change of Registration (Drop/Add) Late registration for returning students begins
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TIME Tuesday, September 16, 2025
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CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL
CALENDAR University Academic Calendar
Sep
24
SPREE Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Wednesday, September 24, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Sep
26
EES Seminar- Levia Straka
McCormick - Civil and Environmental Engineering (CEE)
2:00 PM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Friday, September 26, 2025 at 2:00 PM - 3:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Sep
29
AED-MPM Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Monday, September 29, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
1
SPREE Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Wednesday, October 1, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
3
EES Seminar- Hee-Deung Park
McCormick - Civil and Environmental Engineering (CEE)
2:00 PM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Friday, October 3, 2025 at 2:00 PM - 3:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
6
AED-MPM Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Monday, October 6, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
8
SPREE Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Wednesday, October 8, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
10
EES Seminar- Benjamin Barrios Cerda
McCormick - Civil and Environmental Engineering (CEE)
2:00 PM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Friday, October 10, 2025 at 2:00 PM - 3:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
11
CEE Career Fair
McCormick - Civil and Environmental Engineering (CEE)
9:00 AM Louis Room, Norris University Center
EVENT DETAILS
Civil and Environmental Engineering Career Fair.
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TIME Saturday, October 11, 2025 at 9:00 AM - 12:00 PM
LOCATION Louis Room, Norris University Center    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
13
AED-MPM Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Monday, October 13, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
15
SPREE Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Wednesday, October 15, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
17
Jimmy Quon Lecture: Valorizing Gas Streams Containing CO2 and CO- Bruce Rittman
McCormick - Civil and Environmental Engineering (CEE)
2:00 PM A230, Technological Institute
EVENT DETAILS
Abstract: Carbon dioxide (CO2) is the most important greenhouse gas, and carbon monoxide (CO) is acutely toxic. Release of these gases must be halted. One promising approach is microbiological valorization of CO2 and CO in off-gas streams. Valorization means converting the CO2 or CO to valuable organic compounds that are feedstock for the chemical and energy industries. This talk describes two distinctly different examples of valorization. The first example is valorizing the CO2 in digester biogas using photosynthetic microalgae. The benefits are to generate more methane (CH4) while converting the biogas (~65% CH4) to higher-value biomethane (>97% CH4). The second example is conversion of syngas (a mixture of CO, CO2, and hydrogen (H2)) to organic acids and alcohols using CO-fermenting and chain-elongating bacteria.
Bio: Dr. Bruce E. Rittmann is Regents Professor of Environmental Engineering and Director of the Biodesign Swette Center for Environmental Biotechnology at Arizona State University. His research focuses on the science and engineering needed to “manage microbial communities to provide services to society.” Services include generating renewable energy, cleaning water and soil, and improving human health. Dr. Rittmann is a member of the National Academy of Engineering; a Fellow of AAAS, WEF, IWA, AEESP, and NAI; and a Distinguished Member of ASCE. Dr. Rittmann was awarded the first Clarke Prize for Outstanding Achievements in Water Science and Technology from the NWRI, the Walter Huber Research Prize and the Simon Freese Award from ASCE, the G.M. Fair Award from AAEES, the Perry L. McCarty/AEESP Founders Award, and the Camp Applied Research Award from WEF. He is the co-winner of the 2018 Stockholm Water Prize. Dr. Rittmann has published over 880 journal articles, books, and book chapters, and he has 25 patents. With Dr. Perry McCarty, Dr. Rittmann co-authored the textbook Environmental Biotechnology: Principles and Applications (McGraw-Hill Book Co.), which is now out in its second edition.
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TIME Friday, October 17, 2025 at 2:00 PM - 3:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
20
AED-MPM Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Monday, October 20, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
22
SPREE Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Wednesday, October 22, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
24
EES Seminar- Adductomics: A New Tool in the Exposomics Toolbox- Bill Funk
McCormick - Civil and Environmental Engineering (CEE)
2:00 PM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Friday, October 24, 2025 at 2:00 PM - 3:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
Oct
27
AED-MPM Seminar
McCormick - Civil and Environmental Engineering (CEE)
11:00 AM A230, Technological Institute
EVENT DETAILS
TBA
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TIME Monday, October 27, 2025 at 11:00 AM - 12:00 PM
LOCATION A230, Technological Institute    map it
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CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL
CALENDAR McCormick - Civil and Environmental Engineering (CEE)
 
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