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  • Oct
    2

    EES Seminar: Chris Henry

    McCormick - Civil and Environmental Engineering

    2:00 PM

    EVENT DETAILS

    Integrating Multi-omics Data to Understand Complex Isolate and Microbiome Systems

    Increasingly multi-omics data is becoming more accessible for the study of a wide range of complex biological systems. Today, terabase-scale metagenomes can be readily obtained from soil microbiome systems, while the instruments and protocols surrounding the collection of metabolomic and proteomic data are constantly improving. Yet analysis methods still struggle to annotate these individual datasets, let alone combine them to discover new biological principles. For example, one of the great challenges associated with the use and interpretation of metabolomics data is the large portion of observed peaks that cannot be readily associated with known biochemical compounds. With the lack of clear identities for peaks, and with many identified peaks lacking known pathways, analysis is often limited to correlations alone. In this talk, we will discuss tools and workflows that have been integrated into the DOE Systems-biology Knowledgebase (KBase) to permit the combination of metabolomic and genomic data to present mechanistic explanations for correlations observed in microbiome systems. For example, we will show how exometabolite data from an isolate of Pseudomonas led to an explanation for the widely conserved correlation observed between betaine and pseudomonas in many environments (see Figure 1). We will also explore how these tools are leading to improved annotations of metabolomic data, improved understanding of spontaneous chemistry, and overall a dramatically improved capacity to produce mechanistic explanations for the metabolites observed in biological systems ranging from the JCVI minimal genome to large-scale soil microbiomes.

    Bio
    Dr. Christopher Henry is a scientist at Argonne National Laboratory and co-PI of the DOE Systems Biology Knowledgebase (KBase) project. He is an expert in genome and metagenome annotation, metabolic model reconstruction, and the application of metabolic models to integrate multi-omics data. He has developed numerous frameworks and tools for building models from genomic and metagenomic data and refining models to better match experimental observations, working with systems ranging from cultured isolates to large-scale soil microbiomes.

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    TIME Friday, October 2, 2020 at 2:00 PM - 3:00 PM

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    CONTACT Tierney Acott    tierney.acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • Sep
    8

    Welcome & Breakfast for New McCormick PhD Students

    McCormick School of Engineering and Applied Science

    9:00 AM LR2 & Tech East Plaza, Technological Institute

    EVENT DETAILS

    TIME Monday, September 8, 2025 at 9:00 AM - 10:00 AM

    LOCATION LR2 & Tech East Plaza, Technological Institute    map it

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    CONTACT Andi Joppie    andi.joppie@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Sep
    12

    New Undergraduate Fall 2025 Registration

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Friday, September 12, 2025

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Sep
    15

    Welcome & Luncheon for New Full-time Graduate Students

    McCormick School of Engineering and Applied Science

    11:00 AM Ryan Auditorium & Tech East Plaza, Technological Institute

    EVENT DETAILS

    TIME Monday, September 15, 2025 at 11:00 AM - 12:30 PM

    LOCATION Ryan Auditorium & Tech East Plaza, Technological Institute    map it

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    CONTACT Andi Joppie    andi.joppie@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Sep
    16

    Fall Classes Begin. Change of Registration (Drop/Add) Late registration for returning students begins

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Tuesday, September 16, 2025

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Sep
    24

    SPREE Seminar

    McCormick - Civil and Environmental Engineering (CEE)

    11:00 AM A230, Technological Institute

    EVENT DETAILS

    TIME Wednesday, September 24, 2025 at 11:00 AM - 12:00 PM

    LOCATION A230, Technological Institute    map it

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    CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering (CEE)

  • Sep
    26

    EES Seminar

    McCormick - Civil and Environmental Engineering (CEE)

    2:00 PM A230, Technological Institute

    EVENT DETAILS

    TIME Friday, September 26, 2025 at 2:00 PM - 3:00 PM

    LOCATION A230, Technological Institute    map it

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    CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering (CEE)

  • Sep
    29

    AED-MPM Seminar

    McCormick - Civil and Environmental Engineering (CEE)

    11:00 AM A230, Technological Institute

    EVENT DETAILS

    TIME Monday, September 29, 2025 at 11:00 AM - 12:00 PM

    LOCATION A230, Technological Institute    map it

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    CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering (CEE)

  • Oct
    1

    SPREE Seminar

    McCormick - Civil and Environmental Engineering (CEE)

    11:00 AM A230, Technological Institute

    EVENT DETAILS

    TIME Wednesday, October 1, 2025 at 11:00 AM - 12:00 PM

    LOCATION A230, Technological Institute    map it

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    CONTACT Andrew Liguori    andrew.liguori@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering (CEE)