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  • Apr
    2

    BME Seminar Series - Dr. Andrés García

    McCormick - Biomedical Engineering Department (BME)

    4:00 PM L211, Technological Institute

    EVENT DETAILSmore info

    Bioengineered Hydrogels for Regenerative Medicine

    Abstract

    Hydrogels, highly hydrated cross-linked polymer networks, have emerged as powerful synthetic analogs of extracellular matrices for basic cell studies as well as promising biomaterials for regenerative medicine applications. A critical advantage of these synthetic matrices over natural networks is that bioactive functionalities, such as cell adhesive sequences and growth factors, can be incorporated in precise densities while the substrate mechanical properties are independently controlled. We have engineered poly(ethylene glycol) [PEG]-maleimide hydrogels for local delivery of therapeutic proteins and cells in several regenerative medicine applications. For example, synthetic hydrogels with optimal biochemical and biophysical properties have been engineered to direct human stem cell-derived intestinal organoid growth and differentiation, and these biomaterials serve as injectable delivery vehicles that promote organoid engraftment and repair of intestinal wounds. In another application, hydrogels presenting immunomodulatory proteins induce immune acceptance of allogeneic pancreatic islets and reverse hyperglycemia in models of type 1 diabetes. Finally, photopatterned hydrogel-based microfluidic platforms have been developed using human organoids to model lymphoid-gut interactions. These studies establish these biofunctional hydrogels as promising platforms for basic science studies and biomaterial carriers for cell delivery, engraftment and enhanced tissue repair.

    Bio

    Andrés J. García is the Executive Director of the Petit Institute for Bioengineering and Bioscience and Regents’ Professor at the Georgia Institute of Technology. Dr. García’s research program integrates innovative engineering, materials science, and cell biology concepts and technologies to create cell-instructive biomaterials for regenerative medicine and generate new knowledge in mechanobiology. This cross-disciplinary effort has resulted in innovative biomaterial platforms that elicit targeted cellular responses and tissue repair, human stem cell technologies, and mechanistic insights into the interplay of mechanics and cell biology. In addition, his research has generated intellectual property and licensing agreements with start-up and multi-national companies. He is a co-founder of 5 start-up companies. He has received several distinctions, including the Young Investigator Award, the Clemson Award for Basic Science, and the Founders Award from the Society for Biomaterials; the International Award from the European Society for Biomaterials; the Biomaterials Global Impact Award; and Georgia Tech’s Outstanding Interdisciplinary Activities Award and the Class of 1934 Distinguished Professor Award. He is an elected Fellow of Biomaterials Science and Engineering, Fellow of the American Association for the Advancement of Science, Fellow of the American Society of Mechanical Engineers, and Fellow of the American Institute for Medical and Biological Engineering. He served as President for the Society for Biomaterials in 2018-2019. He is an elected member of the National Academy of Engineering, the National Academy of Medicine, and the National Academy of Inventors.

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    TIME Thursday, April 2, 2026 at 4:00 PM - 5:00 PM

    LOCATION L211, Technological Institute    map it

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    CONTACT BME Administrator    bme-administrator@northwestern.edu EMAIL

    CALENDAR McCormick - Biomedical Engineering Department (BME)

  • Apr
    16

    BME Michael Jaharis Lecture 2026: Dr. Omid Veiseh

    McCormick - Biomedical Engineering Department (BME)

    4:00 PM L211, Technological Institute

    EVENT DETAILS

    TIME Thursday, April 16, 2026 at 4:00 PM - 5:00 PM

    LOCATION L211, Technological Institute    map it

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    CONTACT Jaime Harris    jaime.harris@northwestern.edu EMAIL

    CALENDAR McCormick - Biomedical Engineering Department (BME)

  • Apr
    23

    BME Seminar Series - Dr. Kelly Cross

    McCormick - Biomedical Engineering Department (BME)

    4:00 PM L211, Technological Institute

    EVENT DETAILSmore info

    TIME Thursday, April 23, 2026 at 4:00 PM - 5:00 PM

    LOCATION L211, Technological Institute    map it

    ADD TO CALENDAR

    CONTACT BME Administrator    bme-administrator@northwestern.edu EMAIL

    CALENDAR McCormick - Biomedical Engineering Department (BME)