Dr. Yogesh Goyal
Assistant Professor of Cell and Developmental Biology
Chemical and Biological Engineering & Biomedical Engineering (by courtesy)
“Individual cells within genetically homogenous populations can respond differently to inductive signals or cues and adopt distinct fates. We combine novel experimental, computational, and theoretical frameworks to monitor, perturb, model, and ultimately control single-cell variabilities and emergent fate choices in development and disease, including cancer and developmental disorders. Our lab's interdisciplinary research program welcomes artists, biologists, chemists, clinicians, computer scientists, engineers, mathematicians, and physicists to work together and provide unique insights into biological systems.”
Dr. Guillermo Ameer
Professor of Biomedical Engineering & Surgery
Director of Center for Advanced Regenerative Engineering (CARE)
“Our research team develops biomaterials and nanotechnology for regenerative engineering, tissue engineering, medical devices, drug delivery, and cell delivery applications. We pioneered the development of citrate-based antioxidant biomaterials referred to as polydiolcitrates. Our research can be classified into two areas: 1) citrate-based elastomers and composites thereof, and 2) citrate-based injectable biomaterials.”
Dr. Thomas Meade
Professor of Chemistry, Molecular Biosciences, Neurobiology, Biomedical Engineering, & Radiology Director of the Center for Advanced Molecular Imaging
“The Meade Lab research focuses on inorganic coordination chemistry for the study of molecular imaging of in vivo gene expression and intracellular messengers, transition metal enzyme inhibitors, and electronic biosensors. The design, synthesis and physical properties of transition metal and lanthanide coordination complexes are the foundation of our research.”
Dr. Eric Berns
Research Associate Professor of Biomedical Engineering
“Mrksich group’s interests overlap chemistry, biology and engineering, with an emphasis on the design and synthesis of materials that are biologically active and in applications of the materials to relevant problems in the biological and medical sciences. Much of our work uses self-assembled monolayers of alkanethiolates on gold to prepare model surfaces that are structurally defined, yet that can have complex compositions and present the ligands in spatially-organized patterns. We pioneered the design of ‘dynamic substrates’ that present ligands whose activities can be switched on and off in response to electrical or optical signals, particularly for studies that address the responses of adherent cells to changes in the extracellular matrix. These mimics of the extracellular matrix have led the way to the discovery of novel ligands that mediate cell adhesion. We have also developed robust surface chemistries for preparing biochip arrays and that are compatible with new analytical methods for analyzing the arrays.”
