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  • May
    23

    BME Seminar Series: Dr. Lu Wei

    McCormick - Biomedical Engineering Department (BME)

    4:00 PM Tech M345, Technological Institute

    EVENT DETAILSmore info

    "Functional Bond-Selective Microscopy for Subcellular Biology: From Quantitative Imaging and Sensing to Single-Molecule Analysis"

    ABSTRACT:

    Advances in optical spectroscopy and microscopy have revolutionized our understanding in live biological functions at the sub-cellular levels. In this seminar, I will present our recent efforts in developing and applying next-generation bond-selective spectro-microscopy for retrieving functional chemical information in live cells and neurons. I will first discuss the coupling of the stimulated Raman scattering (SRS) imaging, a nonlinear Raman imaging modality, with newly developed biorthogonal chemical strategies for quantitative subcellular analysis of protein aggregates in neurodegenerative diseases and for intracellular local environmental sensing through alkyne- hydrogen–deuterium exchange (Alkyne-HDX). I will then present a new mid-infrared near-infrared double-resonance imaging technique, BonFIRE, for bond-selective fluorescence imaging with single-molecule sensitivity. This microscopy platform should allow new capabilities for wide-field super-multiplex imaging and vibrational life-time imaging for sensing heterogeneous cellular interactions and environment.

    BIO:

    Lu obtained her Ph.D. from Columbia University in 2015 and joined the faculty at Caltech as an Assistant Professor of Chemistry in 2018. Her group works on developing and applying next-generation vibrational imaging techniques to quantitatively investigate the intracellular biophysical and biochemical processes with an emphasis on neuronal metabolism; multiplex live-cell imaging; functional vibrational imaging and sensing with down to single molecule sensitivity. Lu has been recently recognized by the 2020 NIH Director's New Innovator Award, the 2022 Sloan Research Fellowship, the 2022 Vallee Scholar Award, the 2023 NSF CAREER award, and the 2024 BPS Margaret Oakley Dayhoff Award. Lu is also a Heritage Medical Research Institute (HMRI) Investigator at Caltech.

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    TIME Thursday, May 23, 2024 at 4:00 PM - 5:00 PM

    LOCATION Tech M345, Technological Institute    map it

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    CONTACT Naomi Vasciannie    naomi.vasciannie@northwestern.edu EMAIL

    CALENDAR McCormick - Biomedical Engineering Department (BME)

  • Jun
    19

    Juneteenth (no classes)

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Wednesday, June 19, 2024

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Aug
    14

    Undergraduate Quantum Summer School

    McCormick School of Engineering and Applied Science

    All Day Ford Motor Company Engineering Design Center

    EVENT DETAILSmore info

    TIME Wednesday, August 14, 2024

    LOCATION Ford Motor Company Engineering Design Center    map it

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    CONTACT Dongyang Li    lidongyang@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Aug
    15

    Undergraduate Quantum Summer School

    McCormick School of Engineering and Applied Science

    All Day Ford Motor Company Engineering Design Center

    EVENT DETAILSmore info

    TIME Thursday, August 15, 2024

    LOCATION Ford Motor Company Engineering Design Center    map it

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    CONTACT Dongyang Li    lidongyang@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Sep
    24

    Fall 2024 Classes Begin

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Tuesday, September 24, 2024

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Sep
    30

    Last day to add or change classes (Last day for tuition adjustment related to enrollment changes (to or from full-time). No reductions are made to bills for dropped or swapped classes after this date)

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Monday, September 30, 2024

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar

  • Dec
    7

    Fall classes end

    University Academic Calendar

    All Day

    EVENT DETAILS

    TIME Saturday, December 7, 2024

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    CONTACT Office of the Registrar    nu-registrar@northwestern.edu EMAIL

    CALENDAR University Academic Calendar