BME 465: Biomechanical Modeling & Simulation of Human Movement



BME 465 is designed to familiarize the student with the development, application, and analysis of biomechanical models to simulate motion and orient the graduate student to the skill sets necessary to perform graduate level research projects involving biomechanical modeling and computer simulation of human movement.

The focus of this course is the musculoskeletal system; the course introduces the components of a musculoskeletal model, illustrates how these components are integrated together, and demonstrates the value of and challenges associated with computer simulation of movement. Learning is achieved through a series of lectures, journal article presentations, discussion board assignments, and computer simulation exercises.

Who Takes It?

BME 465 is a graduate course and is intended for first year graduate students. More senior graduate students whose PhD research has evolved to include biomechanical modeling also enroll. Seniors who have been accepted in the BS/MS program enroll as a part of their course requirements for their MS degree. BME 465 is offered in Spring Quarter to ensure first year graduate students without previous experience in dynamics or the biomechanics of movement have the opportunity to complete ME 314 Theory of Machines – Dynamics and BME 366 Biomechanics of Movement before enrolling in BME 465. Prior to taking this course students should have had previous experience with:

  • Free-body diagrams and classical (Newtonian) mechanics
  • Vector analysis, linear algebra, differential equations
  • Statics and dynamics (beyond introductory material such as EA2)
  • Programming and MATLAB
  • Neuromuscular mechanics and physiology


  • Derivation of the equations of motion for simple biomechanical systems
  • Musculoskeletal geometry
  • Implementation of the Hill muscle model in biomechanical simulations of movement