BME 309-0 : Biomedical Systems Analysis (1.25 Unit)

Quarter Offered

Spring : MWF 2:00-2:50pm; Lab MW 3:00-4:20pm, O'Neill ; Tresch


Prerequisites: BMD_ENG 207-0 (can also be taken concurrently); BMD_ENG 308-0; BMD_ENG 220-0, IEMS 303-0, or MECH_ENG 359-0; GEN_ENG 205-4


When studying biological systems, we are often interested in how the output of the system is related to an input; e.g. how insulin secretion is related to glucose levels or how neural activity is related to upcoming movements. This input/output relationship is determined by the dynamics of the system.  These dynamics can be analyzed using a number of different approaches, including explicit equations, computational simulations, or direct experimental measurements.  This course presents approaches for performing such analyses, providing students ‘hands-on’ experience working these methods through a combination of lectures and laboratories.

Who takes it?

This course is taken by junior-level biomedical engineers.  Prerequisites: BMD_ENG 308-0; BMD_ENG 207-0. This course serves as the foundation for future engineering courses across disciplines, including analog and digital signal processing, control theory, system dynamics, and nonlinear systems – as well as for senior Capstone Design (BME 390-1,2).


  • Signal manipulation
  • Linear systems
  • Discrete and continuous-time
  • Convolution
  • Laplace Transform
  • Bode plots
  • Filter design
  • Z-Transform
  • Sampling

Required Class Materials

Signals and Systems: Theory and Applications, Ulaby and Yagle. 

Free pdf available at