1. Donello JE, Banerjee P, Li YX, Guo YX, Yoshtiake T, Zhang XL, Miry O, Kehr J, Stanton PPK, Gross AL, Burgdorf JS, Kroes RA, Moskal JR. Positive N-methyl-D-aspartate receptor modulation by Rapastinel promotes rapid and sustained antidepressant-like effects. Int J Neuropsychopharmacol. 2019; 22(3):247-259. [PDF]
  2. Ghoreishi-Haack N, Priebe JM, Aguado JD, Colechio EM, Burgdorf JS, Bowers MS, Cearley CN, Khan MA, Moskal JR. NYX-2925 is a novel N-methyl-D-aspartate receptor modulator that induces rapid and long-lasting analgesia in rat models of neuropathic pain. J Pharmacol Exp Ther. 2018; 366(3):485-497. [PDF]
  3. Khan MA, Houck DR, Gross AL, Zhang XL, Cearley C, Madsen TM, Kroes RA, Stanton PK, Burgdorf J, Moskal JR. NYX-2925 is a novel NMDA receptor-specific spirocyclic-β-lactam that modulates synaptic plasticity processes associated with learning and memory. Int J Neuropsychopharmacol. 2018; 21(3):242-254. [PDF]
  4. Burgdorf J, Colechio EM, Ghoreishi-Haack N, Gross AL, Rex CS, Zhang XL, Stanton PK, Kroes RA, Moskal JR. IGFBP2 produces rapid-acting and long-lasting effects in rat models of posttraumatic stress disorder via a novel mechanism associated with structural plasticity. Int J Neuropsychopharmacol. 2017; 20(6):476-484. [PDF]
  5. Burgdorf J, Colechio EM, Stanton P, Panksepp J. Positive emotional learning induces resilience to depression: A role for NMDA receptor-mediated synaptic plasticity. Curr Neuropharmacol. 2017; 15(1):3-10. [PDF]
  6. Burgdorf J, Kroes RA, Moskal JR. Rough-and-tumble play induces resilience to stress in rats. Neuroreport. 2017; 28(17):1122-1126. [PDF]
  7. Moskal JR. Editorial (Thematic selection: 'Glutamatergic-based rapid acting antidepressants: The link to synaptic plasticity'). Curr Neuropharmacol. 2017; 15(1):2. [PDF]
  8. Moskal JR, Burgdorf JS, Stanton PK, Kroes RA, Disterhoft JF, Burch RM, Khan MA. The development of rapastinel (formerly GLYX-13); A rapid acting and long lasting antidepressant. Curr Neuropharmacol. 2017; 15(1):47-56. [PDF]
  9. Kroes RA, Moskal JR. The Role of DNA Methylation in ST6Gal1 Expression in Gliomas. Glycobiology. 2016; 26(12):1271-1283. [PDF]
  10. Rajagopal L, Burgdorf JS, Moskal JR, Meltzer HY. GLYX-13 (rapastinel) ameliorates subchronic phencyclidine- and ketamine-induced declarative memory deficits in mice. Behav Brain Res. 2016; 299:105-10. [PDF]
  11. Rodriguez CI, Zwerling J, Kalanthroff E, Shen H, Filippou M, Jo B, Simpson HB, Burch RM, Moskal JR. Effect of a novel NMDA receptor modulataor, Rapastinel (formerly GLYX-13), in OCD: Proof of concept. Am J Psychiatry. 2016; 173(12):1239-1241. [PDF]
  12. Burgdorf J, Zhang XL, Colechio EM, Ghoreishi-Haack N, Gross A, Kroes RA, Stanton PK, Moskal JR. Insulin-Like Growth Factor I Produces an Antidepressant-Like Effect and Elicits N-Methyl-D-Aspartate Receptor Independent Long-Term Potentiation of Synaptic Transmission in Medial Prefrontal Cortex and Hippocampus. Int J Neuropsychopharmacol. 2015; 19(2), 1-10. [PDF]
  13. Burgdorf J, Zhang XL, Weiss C, Gross A, Boikess SR, Kroes RA, Khan MA, Burch RM, Rex CS, Disterhoft JF, Stanton PK, Moskal JR. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 2015; 308:202-11. [PDF]
  14. Wildburger NC, Zhou S, Zacharias LG, Kroes RA, Moskal JR, Schmidt M, Mirzaei P, Gumin J, Lang FF, Mechref Y, Nilsson CL. Integrated Transcriptomic and Glycomic Profiling of Glioma Stem Cell Xenografts. J Proteome Res. 2015; 14(9):3932-9. [PDF]
  15. Horvatovich P, Lundberg EK, Chen YJ, Sung TY, He F, Nice EC, Goode RJ, Yu S, Ranganathan S, Baker MS, Domont GB, Velasquez E, Li D, Liu S, Wang Q, He QY, Menon R, Guan Y, Corrales FJ, Segura V, Casal JI, Pascual-Montano A, Albar JP, Fuentes M, Gonzalez-Gonzalez M, Diez P, Ibarrola N, Degano RM, Mohammed Y, Borchers CH, Urbani A, Soggiu A, Yamamoto T, Salekdeh GH, Archakov A, Ponomarenko E, Lisitsa A, Lichti CF, Mostovenko E, Kroes RA, Rezeli M, Végvári Á, Fehniger TE, Bischoff R, Vizcaíno JA, Deutsch EW, Lane L, Nilsson CL, Marko-Varga G, Omenn GS, Jeong SK, Lim JS, Paik YK, Hancock WS. Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project. J Proteome Res. 2015;14(9):3415-31. [PDF]
  16. Basu S, Ma R, Moskal JR, Basu M. Regulations of glycolipid: XI. glycosyltransferase (GSL: GLTs) genes involved in SA-LeX and related GSLs biosynthesis in carcinoma cells by Biosimilar apoptotic agents: potential anticancer drugs. Adv Exp Med Biol. 2015; 842:329-54. [PDF]
  17. Burgdorf J, Kroes RA, Zhang XL, Gross AL, Schmidt M, Weiss C, Disterhoft JF, Burch RM, Stanton PK, Moskal JR. Rapastinel (GLYX-13) has therapeutic potential for the treatment of post-traumatic stress disorder: characterization of a NMDA receptor-mediated metaplasticity process in the medial prefrontal cortex of rats. Behav Brain Res. 2015; 294:177-85. [PDF]
  18. Nilsson CL, Mostovenko E, Lichti CF, Ruggles K, Fenyö D, Rosenbloom KR, Hancock WS, Paik YK, Omenn GS, LaBaer J, Kroes RA, Uhlén M, Hober S, Végvári Á, Andrén PE, Sulman EP, Lang FF, Fuentes M, Carlsohn E, Emmett MR, Moskal JR, Berven FS, Fehniger TE, Marko-Varga G. Use of ENCODE resources to characterize novel proteoforms and missing proteins in the human proteome. J Proteome Res. 2015;14(2):603-8. [PDF]
  19. Lichti CF, Liu H, Shavkunov AS, Mostovenko E, Sulman EP, Ezhilarasan R, Wang Q, Kroes RA, Moskal JC, Fenyö D, Oksuz BA, Conrad CA, Lang FF, Berven FS, Végvári A, Rezeli M, Marko-Varga G, Hober S, Nilsson CL. Integrated chromosome 19 transcriptomic and proteomic data sets derived from glioma cancer stem-cell lines. J Proteome Res. 2014;13(1):191-9. [PDF]
  20. Moskal JR, Burch R, Burgdorf JS, Kroes RA, Stanton PK, Disterhoft JF, Leander JD. GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists. Expert Opin Investig Drugs. 2014; 23(2):243-54. [PDF]
  21. Lau JC, Kroes RA, Moskal JR, Linsenmeier RA. Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina. Mol Vis. 2013;19:1538-53. [PDF]
  22. Emmett MR, Kroes RA, Moskal JR, Conrad CA, Priebe W, Laezza F, Meyer-Baese A,  Nilsson CL. Integrative biological analysis for neuropsychopharmacology. Neuropsychopharmacology. 2014;39(1):5-23. [PDF]
  23. Burgdorf J, Moskal JR, Brudzynski SM, Panksepp J. Rats selectively bred for low levels of play-induced 50 kHz vocalizations as a model for autism spectrum disorders: a role for NMDA receptors. Behav Brain Res. 2013;251:18-24. [PDF]
  24. Burgdorf J, Zhang XL, Nicholson KL, Balster RL, Leander JD, Stanton PK, Gross AL, Kroes RA, Moskal JR. GLYX-13, a NMDA receptor glycine-site functional partial agonist, induces antidepressant-like effects without ketamine-like side effects. Neuropsychopharmacology. 2013; 38(5):729-42. [PDF]
  25. Nilsson CL, Berven F, Selheim F, Liu H, Moskal JR, Kroes RA, Sulman EP, Conrad CA, Lang FF, Andrén PE, Nilsson A, Carlsohn E, Lilja H, Malm J, Fenyö D, Subramaniyam D, Wang X, Gonzales-Gonzales M, Dasilva N, Diez P, Fuentes M, Végvári Á, Sjödin K, Welinder C, Laurell T, Fehniger TE, Lindberg H, Rezeli M, Edula G, Hober S, Marko-Varga G. Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium. J Proteome Res. 2013;12(1):135-50. [PDF]
  26. Srivastava DP, Jones KA, Woolfrey KM, Burgdorf J, Russell TA, Kalmbach A, Lee H, Yang C, Bradberry MM, Wokosin D, Moskal JR, Casanova MF, Waters J, Penzes P. Social, communication, and cortical structural impairments in Epac2-deficient mice. J Neurosci. 2012;32(34):11864-78. [PDF]
  27. Basu S, Ma R, Moskal JR, Basu M, Banerjee S. Apoptosis of breast cancer cells: modulation of genes for glycoconjugate biosynthesis and targeted drug delivery. Adv Exp Med Biol. 2012;749:233-55. [PDF]
  28. McKay BM, Oh MM, Galvez R, Burgdorf J, Kroes RA, Weiss C, Adelman JP, Moskal  JR, Disterhoft JF. Increasing SK2 channel activity impairs associative learning.  J Neurophysiol. 2012;108(3):863-70. [PDF]
  29. Basu S, Ma R, Moskal JR, Basu M. Ganglioside biosynthesis in developing brains and apoptotic cancer cells: X. regulation of glyco-genes involved in GD3 and Sialyl-Lex/a syntheses. Neurochem Res. 2012;37(6):1245-55. [PDF]
  30. Webber ES, Harmon KM, Beckwith TJ, Peña S, Burgdorf J, Panksepp J, Cromwell HC. Selective breeding for 50 kHz ultrasonic vocalization emission produces alterations in the ontogeny and regulation of rough-and-tumble play. Behav Brain Res. 2012;229(1):138-44. [PDF]
  31. Brudzynski SM, Gibson B, Silkstone M, Burgdorf J, Kroes RA, Moskal JR, Panksepp J. Motor and locomotor responses to systemic amphetamine in three lines  of selectively bred Long-Evans rats. Pharmacol Biochem Behav. 2011;100(1):119-24. [PDF]
  32. Corcoran ME, Kroes RA, Burgdorf JS, Moskal JR. Regional changes in gene expression after limbic kindling. Cell Mol Neurobiol. 2011;31(6):819-34. [PDF]
  33. Burgdorf J, Panksepp J, Moskal JR. Frequency-modulated 50 kHz ultrasonic vocalizations: a tool for uncovering the molecular substrates of positive affect. Neurosci Biobehav Rev. 2011;35(9):1831-6. [PDF]
  34. Burgdorf J, Kroes RA, Weiss C, Oh MM, Disterhoft JF, Brudzynski SM, Panksepp J, Moskal JR. Positive emotional learning is regulated in the medial prefrontal cortex by GluN2B-containing NMDA receptors. Neuroscience. 2011; 192:515-23. [PDF]
  35. Burgdorf J, Zhang XL, Weiss C, Matthews E, Disterhoft JF, Stanton PK, Moskal JR. The N-methyl-D-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats. Neurobiol Aging. 2011; 32(4):698-706. [PDF] 
  36. Moskal JR, Burgdorf J, Kroes RA, Brudzynski SM, Panksepp J. A novel NMDA receptor glycine-site partial agonist, GLYX-13, has therapeutic potential for the treatment of autism. Neurosci Biobehav Rev. 2011; 35(9):1982-8. [PDF]
  37. Brudzynski SM, Silkstone M, Komadoski M, Scullion K, Duffus S, Burgdorf J, Kroes RA, Moskal JR, Panksepp J. Effects of intraaccumbens amphetamine on production of 50 kHz vocalizations in three lines of selectively bred Long-Evans rats. Behav Brain Res. 2011;217(1):32-40. [PDF]
  38. Kroes RA, He H, Emmett MR, Nilsson CL, Leach FE 3rd, Amster IJ, Marshall AG, Moskal JR. Overexpression of ST6GalNAcV, a ganglioside-specific alpha2,6-sialyltransferase, inhibits glioma growth in vivo. Proc Natl Acad Sci U S A. 2010;107(28):12646-51. [PDF]
  39. Burgdorf J, Kroes RA, Beinfeld MC, Panksepp J, Moskal JR. Uncovering the molecular basis of positive affect using rough-and-tumble play in rats: a role for insulin-like growth factor I. Neuroscience. 2010;168(3):769-77. [PDF]
  40. He H, Nilsson CL, Emmett MR, Marshall AG, Kroes RA, Moskal JR, Ji Y, Colman H, Priebe W, Lang FF, Conrad CA. Glycomic and transcriptomic response of GSC11 glioblastoma stem cells to STAT3 phosphorylation inhibition and serum-induced differentiation. J Proteome Res. 2010;9(5):2098-108. [PDF]
  41. Moskal JR, Kroes RA, Dawson G. The glycobiology of brain tumors: disease relevance and therapeutic potential. Expert Rev Neurother. 2009;9(10):1529-45. [PDF]
  42. He H, Nilsson CL, Emmett MR, Ji Y, Marshall AG, Kroes RA, Moskal JR, Colman H, Lang FF, Conrad CA. Polar lipid remodeling and increased sulfatide expression  are associated with the glioma therapeutic candidates, wild type p53 elevation and the topoisomerase-1 inhibitor, irinotecan. Glycoconj J. 2010;27(1):27-38. [PDF]
  43. Crosson LA, Kroes RA, Moskal JR, Linsenmeier RA. Gene expression patterns in hypoxic and post-hypoxic adult rat retina with special reference to the NMDA receptor and its interactome. Mol Vis. 2009;15:296-311. [PDF]
  44. Ma R, Matthew Decker N, Anilus V, Moskal JR, Burgdorf J, Johnson JR, Basu M,  Banerjee S, Basu S. Post-translational and transcriptional regulation of glycolipid glycosyltransferase genes in apoptotic breast carcinoma cells: VII. Studied by DNA-microarray after treatment with L-PPMP. Glycoconj J. 2009;26(6):647-61. [PDF]
  45. Burgdorf J, Kroes RA, Moskal JR, Pfaus JG, Brudzynski SM, Panksepp J. Ultrasonic vocalizations of rats (Rattus norvegicus) during mating, play, and aggression: Behavioral concomitants, relationship to reward, and self-administration of playback. J Comp Psychol. 2008;122(4):357-67. [PDF]
  46. Burgdorf J, Panksepp J, Brudzynski SM, Beinfeld MC, Cromwell HC, Kroes RA, Moskal JR. The effects of selective breeding for differential rates of 50-kHz ultrasonic vocalizations on emotional behavior in rats. Dev Psychobiol. 2009;51(1):34-46. [PDF]
  47. Harmon KM, Cromwell HC, Burgdorf J, Moskal JR, Brudzynski SM, Kroes RA, Panksepp J. Rats selectively bred for low levels of 50 kHz ultrasonic vocalizations exhibit alterations in early social motivation. Dev Psychobiol. 2008;50(4):322-31. [PDF]
  48. Wang H, Liang S, Burgdorf J, Wess J, Yeomans J. Ultrasonic vocalizations induced by sex and amphetamine in M2, M4, M5 muscarinic and D2 dopamine receptor  knockout mice. PLoS One. 2008;3(4):e1893. [PDF]
  49. Panksepp J, Burgdorf J, Beinfeld MC, Kroes RA, Moskal JR. Brain regional neuropeptide changes resulting from social defeat. Behav Neurosci. 2007;121(6):1364-71. [PDF]
  50. Kroes RA, Dawson G, Moskal JR. Focused microarray analysis of glyco-gene expression in human glioblastomas. J Neurochem. 2007;103 Suppl 1:14-24. [PDF]
  51. Wood PL, Khan MA, Moskal JR. Mechanism of action of the disease-modifying anti-arthritic thiol agents D-penicillamine and sodium aurothiomalate: restoration of cellular free thiols and sequestration of reactive aldehydes. Eur  J Pharmacol. 2008;580(1-2):48-54. [PDF]
  52. Wood PL, Khan MA, Moskal JR. Cellular thiol pools are responsible for sequestration of cytotoxic reactive aldehydes: central role of free cysteine and cysteamine. Brain Res. 2007;1158:158-63. [PDF]
  53. Kroes RA, Burgdorf J, Otto NJ, Panksepp J, Moskal JR. Social defeat, a paradigm of depression in rats that elicits 22-kHz vocalizations, preferentially activates the cholinergic signaling pathway in the periaqueductal gray. Behav Brain Res. 2007;182(2):290-300. [PDF]
  54. Burgdorf J, Wood PL, Kroes RA, Moskal JR, Panksepp J. Neurobiology of 50-kHz  ultrasonic vocalizations in rats: electrode mapping, lesion, and pharmacology studies. Behav Brain Res. 2007;182(2):274-83. [PDF]
  55. Wood PL, Khan MA, Moskal JR. The concept of "aldehyde load" in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line. Brain Res. 2007;1145:150-6. [PDF]
  56. Wood PL, Khan MA, Moskal JR, Todd KG, Tanay VA, Baker G. Aldehyde load in ischemia-reperfusion brain injury: neuroprotection by neutralization of reactive aldehydes with phenelzine. Brain Res. 2006;1122(1):184-90. [PDF]
  57. Moskal JR, Kroes RA, Otto NJ, Rahimi O, Claiborne BJ. Distinct patterns of gene expression in the left and right hippocampal formation of developing rats. Hippocampus. 2006;16(8):629-34. [PDF]
  58. Wood PL, Khan MA, Kulow SR, Mahmood SA, Moskal JR. Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines. Brain Res. 2006;1095(1):190-9. [PDF]
  59. Wood PL, Khan MA, Moskal JR. Neurochemical analysis of amino acids, polyamines and carboxylic acids: GC-MS quantitation of tBDMS derivatives using ammonia positive chemical ionization. J Chromatogr B Analyt Technol Biomed Life Sci. 2006;831(1-2):313-9. [PDF]
  60. Kroes RA, Panksepp J, Burgdorf J, Otto NJ, Moskal JR. Modeling depression: social dominance-submission gene expression patterns in rat neocortex. Neuroscience. 2006;137(1):37-49. [PDF]
  61. Burgdorf J, Panksepp J, Beinfeld MC, Kroes RA, Moskal JR. Regional brain cholecystokinin changes as a function of rough-and-tumble play behavior in adolescent rats. Peptides. 2006;27(1):172-7. [PDF]
  62. Burgdorf J, Panksepp J. The neurobiology of positive emotions. Neurosci Biobehav Rev. 2006;30(2):173-87. [PDF]
  63. Burgdorf J, Panksepp J, Brudzynski SM, Kroes R, Moskal JR. Breeding for 50-kHz positive affective vocalization in rats. Behav Genet. 2005;35(1):67-72. [PDF]
  64. Panksepp J, Burgdorf J, Beinfeld MC, Kroes RA, Moskal JR. Regional brain cholecystokinin changes as a function of friendly and aggressive social interactions in rats. Brain Res. 2004;1025(1-2):75-84. [PDF]
  65. Dawson G, Moskal JR, Dawson SA. Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death. J Neurochem. 2004;89(6):1436-44. [PDF]