EVENT DETAILS
Weekly seminars with guest speakers.
Thursdays 9:00AM - 10:00AM Tech M345
Hang LuGeorgia TechHost: Luis Amaral
A Chemical Engineering's Approach to Systems Biology - Microfluidics, Automation, and Big-Data
My lab is interested in engineering micro systems and automation tools to address questions in systems neuroscience, developmental biology, and cell biology that are difficult to answer with conventional techniques. Micro technologies provide the appropriate length scale for investigating molecules, cells, and small organisms; moreover, one can also take advantage of unique phenomena associated with small-scale flow and field effects, as well as unprecedented parallelization and automation to gather quantitative and large-scale data about complex biological systems. I will show how continuous flow, multi-phase flow, and open microfluidic systems can be used to culture, manipulate, image, and stimulate samples. I will show how image informatics and statistical machine learning techniques can greatly enhance our ability to understand the information carried in images and video microscopy data. We apply these techniques to address a variety of questions in developmental and behavioral neurogenetics, and aging in a soil nematode C. elegans, which have implications in human developmental, psychiatric, and age-related neural disorders.
Hang Lu is the Love Family Professor in the School of Chemical and Biomolecular Engineering and the Director of the Interdisciplinary Bioengineering Program at Georgia Tech. She graduated summa cum laude from the University of Illinois at Urbana-Champaign in 1998 with a B.S. in Chemical Engineering. She has a Master's degree in Chemical Engineering Practice from MIT (2000). She obtained her Ph.D. in Chemical Engineering in 2003 from MIT. Between 2003 and 2005, she was a postdoc at UCSF and the Rockefeller University in neuroscience. Her current research interests are in microfluidics, automation, quantitative analyses, and their applications in neurobiology, cell biology, cancer, and biotechnology. Her award and honors include the Pioneer of Miniaturization Lectureship, the ACS Analytical Chemistry Young Innovator Award, a National Science Foundation CAREER award, an Alfred P. Sloan Foundation Research Fellowship, a DuPont Young Professor Award, a DARPA Young Faculty Award, Council of Systems Biology in Boston (CSB2) Prize in Systems Biology, Georgia Tech Junior Faculty Teaching Excellence Award, and Georgia Tech Outstanding PhD Thesis Advisor Award; she was also named an MIT Technology Review TR35 top innovator, and invited to give the Rensselaer Polytechnic Institute Van Ness Award Lectures in 2011, and the Saville Lecture at Princeton in 2013. She is an elected fellow of American Association for the Advancement of Science (AAAS) and an elected fellow of the American Institute for Medical and Biological Engineering (AIMBE). She is currently the associate director of the Southeast Center for Mathematics and Biology (SCMB) at Georgia Tech, supported by NSF and Simons Foundation. Her lab's work has been and is supported by >$30M ($15M to her lab) from US NSF, NIH, private foundations and others.
TIME Thursday September 26, 2019 at 9:00 AM - 10:00 AM
LOCATION M345, Technological Institute map it
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CONTACT Elizabeth Rentfro elizabeth.rentfro@northwestern.edu
CALENDAR McCormick-Chemical and Biological Engineering