CHEM_ENG 475: Cell-Material Interactions

Quarter Offered

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This course may be taken by undergraduate students if they are in the Biotechnology Certificate program or by permission of the instructor. Materials are increasingly be applied for biomedical applications, such as prostheses, biosensors, and wound repair. The original idea that materials should be “inert” has been replaced with the idea that materials can have a defined cellular interaction that can promote specific cellular processes. Materials are being designed to provide several types of information to cells in their environment by regulating the mechanical properties, cell-cell interactions, cell-matrix interactions, and the release of soluble factors such as protein or DNA. This course presents the fundamental aspects of these cellular processes, and also the design of biomaterials to promote or block these processes. Critical issues in the field that will be discussed include biocompatibility, cell adhesion and signaling, drug delivery, stem cells, and mechanotransduction.