Research
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Research Areas
Cell and Molecular Engineering

Research in this area harnesses biological components — genes, RNA, enzymes, and lipids — to reveal the engineering principles that underlie function and to build entirely new systems and devices. This program develops new experimental and computational approaches to understand molecular networks in cells and to program cells to perform new functions, including the assembly of biological parts to build new molecular devices, drugs, high value chemicals and to perform bio sensing and drug delivery.

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Cardiovascular

Credit: Fibroblast cells untreated and treated with the drug dexamethasone (Vadim Backman)

Research Topics

Nanomaterials • cell mechanics • bio-optics • stem cell biology and engineering • cell protective and regenerative mechanisms • protective and regenerative engineering • diagnostics • nanotherapy • cardiovascular Immunotherapy • inflammation • targeted delivery • atherosclerosis • Chromatin Engineering

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Drug Delivery and Discovery

Credit: Neha Kamat

Research Topics

Polymersomes • artificial cells • diblock copolymers • SAMDI (mass spectrometry) • cell-free systems • megamolecules • Chromatin Engineering

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Vision and Sensory Systems

Credit: Stress fibers in a Schlemm's canal endothelial cell (Mark Johnson)

Research Topics

Cell Mechanics • glaucoma • schlemm’s canal • sanotherapy • drug delivery • multiscale imaging • visible-light optical coherence tomography (vis-OCT)

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Cancer

Credit: Macromolecular Crowding Studies (Vadim Backman)

Research Topics

Genomics • computational biology • genome engineering • imaging • drug design and delivery • Chromatin Engineering

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Global Health

Credit: Nanofabrication via network self-assembly and collapse (Evan Scott)

Research Topics

Diagnostics • subunit vaccination • chagas disease • tuberculosis • nanocarriers • immunostimulation

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