Research
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Research Areas
Biomaterials and Regenerative Engineering

The Biomaterials Group aims to develop self-assembled, bio-integrated electronic, synthetic, and nanoscale materials for biomedical applications. Research and teaching areas include self-assembled nanostructures, bioelectronics, synthetic biology, bio-membrane dynamics, nanotechnology, controlled drug release, cell-material interactions, immunoengineering and computational analysis of molecular dynamics.

The Regenerative Engineering Group aims to understand the innate mechanisms of cell protection and regeneration and establish engineering strategies for controlling protective and regenerative processes with the ultimate goal of restoring tissue and organ function. Research and teaching areas include genomic analysis, transport biology and engineering, cardiovascular protective engineering, and regenerative engineering.

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Cardiovascular

Credit: Induced pluripotent stem cells (Bin Jiang)

Research Topics

Cardiac patch • cardiac regeneration • vascular graft • vascular stent • vascular regeneration • nanomaterial construction and applications • transport biology • digital biosensors • biofeedback • mechanisms of vascular calcification • stem cell biology and engineering • cell protective and regenerative mechanisms • protective and regenerative engineering • Chromatin Engineering

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Drug Delivery and Discovery

Credit: Self-assembled poly(propylene sulfone) nanoparticles (Evan Scott)

Research Topics

Nanoparticles • immunotherapy • artificial cells • machine learning • protein engineering • high-throughput screening • nanotechnology • nanomaterials • drug development • bioinformatics • synthetic biology • computational analysis

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Rehabilitation

Credit: Millimetre-scale electromechanical systems for sensing of soft-tissue elastic moduli (John Rogers)

Research Topics

Digital biosensors • skin-interfaced wearable devices • data analytics and machine learning • biofeedback • megamolecules • antibody mimics • antibody-drug conjugates • PET imaging agents biology

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Vision and Sensory Systems

Credit: Traction intensity distribution in a Schlemm's canal endothelial cell (Mark Johnson)

Research Topics

Glaucoma • age-related macular degeneration • mass transport • immune modulation • ocular biomechanics • macular degeneration • transport biology • computational modeling

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Cancer

Signaling pathways in breast call transformation (Zhe Ji).

Research Topics

Data science • computational biology • functional genomics • immunostimulatory materials • drug delivery systems • nanotechnology • drug development • immunomodulation • genomic technologies • computational modeling. • megamolecules • antibody mimics • antibody-drug conjugates • PET imaging agents • Chromatin Engineering

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Global Health

Credit: Nanocarrier-enhanced intracellular delivery of benznidazole (Evan Scott)Research Topics

Infectious diseases • vaccines

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