Research Areas
Imaging and Biophotonics

Biophotonics research focuses on the development of optical imaging and sensing technologies to study biomolecule, cell, and tissue structure and function at nanoscopic and microscopic scales. The goals are to improve both fundamental biomedical research and clinical patient care. Translational technologies developed by biophotonics faculty members include, for example, new far-field optical back-scattering spectroscopic imaging to analyze cellular nanoscale alterations in early carcinogenesis and cancer therapies, and new functional imaging to provide high resolution and high sensitivity for managing blinding diseases. Biophotonics faculty members also investigate a variety of fundamental biomedical questions, such as chromatin architecture remodeling in early cancers, intracellular single-molecule interactions, molecular pathways of hypoxia in diabetic eyes, and brain hemodynamic responses to strokes.

The direction of Imaging research is driven by the aim to provide new insights into diseases process of the human body. A focus area is the development of novel Magnetic Resonance Imaging (MRI) imaging technology and integration of advanced data analysis methodology. The goal is to improve diagnosis and therapy planning by developing novel and innovative imaging techniques for the evaluation of tissue morphology, body function, and physiologic processes throughout the human body. Inter-disciplinary collaborations with physicians and scientist at the Feinberg School of Medicine provide an ideal setting for the successful translational research activities.

The research includes new imaging and biphotonic technology development, image based biophysical modeling of disease processes, the application of these techniques to address crucial problems in fundamental biology and human physiology, and translational into clinical applications and patient studies.

Imaging and Biophotonics Faculty

Some faculty specialize in particular research applications within imaging and biophotonics: Cancer, Cardiovascular, Drug Discovery and Delivery, Rehabilitation, and Vision and Ophthalmology. See below for faculty involved in each application.



Drug Discovery and Delivery


Vision and Ophthalmology