BME 325: Introduction to Medical Imaging

Quarter Offered

Fall : 1-1:50 MWF ; Sahakian


The EA math sequence, some Signals and Systems course covering Fourier concepts (co-registration in BME 305 is OK) Note: the text’s Appendix G has a review of Fourier Transforms and Convolution; Physics 135-3 (Fields and Waves), or equivalents, or consent of instructor.


Fundamentals of the four most-important clinical medical imaging modalities: X-ray, Ultrasound, Radionuclide, and MRI.  The primary focus is on the physical principles, instrumentation methods, and imaging algorithms, however the medical interpretation of images, and the clinical, research and ethical issues in medical imaging are also included where possible to give students a deeper understanding of the development and applications of medical imaging.

INSTRUCTOR: Prof. Alan V. Sahakian (Teaching Assistant: Mark Hoggarth

REQUIRED TEXT: 'The Essential Physics of Medical Imaging', Third Edition, J.T. Bushberg, J. A. Seibert, E.M. Leidholdt, J.M. Boone, Publisher: Lippincott, Williams and Wilkins, 2012. (two copies are on reserve at the library).

REFERENCE TEXTS (on reserve at the library):

  • Principles of Medical Imaging, K. Kirk Shung', Michael B. Smith, Benjamin Tsui, Academic Press, 1992.
  • 'Christensen’s Introduction to the Physics of Diagnostic Radiology', Thomas S. Curry, III, James E. Dowdey and Robert C. Murry, Jr., Leigh and Febiger, 1984.

PROJECTS: Each student will individually complete a written report (about fifteen double-spaced pages, including figures and references) on a topic related to the course.  In addition, each Ph.D. student will give a short (about 15 minute) presentation on his or her project during the final week of class. The choice of project topic is left to the student, but students must submit a short (one-page) proposal of their project to the instructor by Friday, October 27 for approval. The report may be a discussion of a new imaging modality, a new development in a classical modality, a new clinical application, an in-depth review of the history of some modality, a detailed technical discussion of some aspect of a modality (perhaps including a MATLAB or other program), a discussion of a clinical or research imaging problem and solutions, or another relevant topic which you find interesting. All students will be responsible for attending the Ph.D. students' oral presentations, as this material will be considered fair game on the final.



  • Homework: 25%,
  • Exam 1: 25%,
  • Project: 25%,
  • Exam 2: 25%