Department Events

Events

  • Jan
    12

    Distribution of Toxic Peptides Produced by Cyanobacteria (a.k.a. "Blue-Green Algae") in Lakes and Their Removal by Drinking Water Treatment Plants

    McCormick - Civil and Environmental Engineering

    2:00 PM A230, Technological Institute

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    Cyanobacterial harmful algal blooms (CHABs) are a growing problem worldwide due to inadequate protections for freshwater resources, poor land management, and in some cases global climate change. Toxins and biomass produced by CHABs present challenges for drinking water production, inhibits use of lakes and rivers for recreation, and alters food web dynamics. This is problematic since in the United States more than 60% of drinking water is produced from freshwaters while recent studies show an increasing number of lakes and rivers are becoming eutrophic, thus capable of supporting CHABs.
    CHAB species produce a fascinating number of secondary metabolites that display various activities in eukaryotic cells. While some are explored for their medicinal purposes others are acutely toxic affecting multiple organs including liver, kidney, reproductive, central and peripheral nervous systems. In particular, cyanobacteria produce a variety of linear and circular peptides that vary widely in their potency and physiological effects. Among these, microcystins and nodularin are well known inhibitors of protein phosphatases causing acute and chronic effects in the liver. Other cyanopeptides including anabaenopeptins, cyanopeptolins, microginins, and aeruginosins inhibit multiple enzymes in eukaryotic cells, primarily serine/threonine proteases. Originally considered non-toxic recent studies indicate some of these are potent neurotoxins.
    The temporal and spatial distribution of cyanopeptide mixtures in CHABs is relatively unknown. CHAB forming species are known to produce multiple cyanopeptide classes in laboratory cultures. Thus it is likely that CHAB events involve multiple toxic and/or bioactive compounds rather than a single toxin. This has important implications for human and environmental health as well as public health monitoring strategies. We have described the spatial and temporal dynamics of cyanopeptides in lakes distributed globally and their removal during drinking water treatment processes. Our results challenge the notion that CHAB events involve a single toxin, but rather involve a complex mixture of compounds whose effects on mammalian cells is relatively unexplored.

    Todd Miller holds a doctorate in Marine Estuarine Environmental Science from the University of Maryland - College Park where he studied organic sulfur metabolizing bacteria (Roseobacter species) associated with marine algae (dinoflagellates). Following graduate school Dr. Miller was a post- doctoral fellow at Johns Hopkins Bloomberg School of Public Health where he studied the fate of antibacterial compounds Triclosan and Triclocarban in estuarine sediments, biodegradation of anthropogenic compounds by bacteria, and genomics of the dioxin degrading bacterium Sphingomonas wittichii. Following Johns Hopkins he did a second post- doctoral fellowship at the University of Wisconsin - Madison at the Center for Limnology and Department of Bacteriology where he studied the ecology of toxic cyanobacteria in freshwater lakes. He is currently an associate professor in the Joseph J. Zilber School of Public Health at the University of Wisconsin - Milwaukee and an affiliate with the School of Freshwater Sciences. His laboratory studies microbial ecology, and environmental chemistry of hazardous bacteria, chemicals, and natural products in aquatic environments.

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    TIME Friday, January 12, 2018 at 2:00 PM - 3:00 PM

    LOCATION A230, Technological Institute    map it

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    CONTACT Tierney Acott    tierney-acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • Apr
    20

    ETOPiA: Copenhagen

    McCormick School of Engineering and Applied Science

    7:30 PM The STAGE Lab, Reynolds Club, 1131 E. 57th St.

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    TIME Friday, April 20, 2018 at 7:30 PM - 9:30 PM

    LOCATION The STAGE Lab, Reynolds Club, 1131 E. 57th St.   

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    CONTACT Tech-IC group    tech-ic@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Apr
    21

    ETOPiA: Copenhagen

    McCormick School of Engineering and Applied Science

    7:30 PM The STAGE Lab, Reynolds Club, 1131 E. 57th St.

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    TIME Saturday, April 21, 2018 at 7:30 PM - 9:30 PM

    LOCATION The STAGE Lab, Reynolds Club, 1131 E. 57th St.   

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    CONTACT Tech-IC group    tech-ic@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Apr
    22

    ETOPiA: Copenhagen

    McCormick School of Engineering and Applied Science

    2:00 PM The STAGE Lab, Reynolds Club, 1131 E. 57th St.

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    TIME Sunday, April 22, 2018 at 2:00 PM - 4:00 PM

    LOCATION The STAGE Lab, Reynolds Club, 1131 E. 57th St.   

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    CONTACT Tech-IC group    tech-ic@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Apr
    25

    SEGIM Seminar: Salvatore Di Bernardo

    McCormick - Civil and Environmental Engineering

    11:00 AM A230, Technological Institute

    EVENT DETAILS

    TIME Wednesday, April 25, 2018 at 11:00 AM - 12:00 PM

    LOCATION A230, Technological Institute    map it

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    CONTACT Tierney Acott    tierney-acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • Apr
    27

    EES Seminar Series: Josiah Hester

    McCormick - Civil and Environmental Engineering

    2:00 PM A230, Technological Institute

    EVENT DETAILS

    TIME Friday, April 27, 2018 at 2:00 PM - 3:00 PM

    LOCATION A230, Technological Institute    map it

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    CONTACT Tierney Acott    tierney-acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • Apr
    27

    ETOPiA: Copenhagen

    McCormick School of Engineering and Applied Science

    7:30 PM The STAGE Lab, Reynolds Club, 1131 E. 57th St.

    EVENT DETAILSmore info

    TIME Friday, April 27, 2018 at 7:30 PM - 9:30 PM

    LOCATION The STAGE Lab, Reynolds Club, 1131 E. 57th St.   

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    CONTACT Tech-IC group    tech-ic@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Apr
    28

    ETOPiA: Copenhagen

    McCormick School of Engineering and Applied Science

    7:30 PM The STAGE Lab, Reynolds Club, 1131 E. 57th St.

    EVENT DETAILSmore info

    TIME Saturday, April 28, 2018 at 7:30 PM - 9:30 PM

    LOCATION The STAGE Lab, Reynolds Club, 1131 E. 57th St.   

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    CONTACT Tech-IC group    tech-ic@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Apr
    29

    ETOPiA: Copenhagen

    McCormick School of Engineering and Applied Science

    2:00 PM The STAGE Lab, Reynolds Club, 1131 E. 57th St.

    EVENT DETAILSmore info

    TIME Sunday, April 29, 2018 at 2:00 PM - 4:00 PM

    LOCATION The STAGE Lab, Reynolds Club, 1131 E. 57th St.   

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    CONTACT Tech-IC group    tech-ic@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • May
    16

    SEGIM Seminar: Claire White

    McCormick - Civil and Environmental Engineering

    11:00 AM A230, Technological Institute

    EVENT DETAILS

    TIME Wednesday, May 16, 2018 at 11:00 AM - 12:00 PM

    LOCATION A230, Technological Institute    map it

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    CONTACT Tierney Acott    tierney-acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering

  • May
    18

    EES Seminar: Jim Griffin

    McCormick - Civil and Environmental Engineering

    2:00 PM A230, Technological Institute

    EVENT DETAILS

    TIME Friday, May 18, 2018 at 2:00 PM - 3:00 PM

    LOCATION A230, Technological Institute    map it

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    CONTACT Tierney Acott    tierney-acott@northwestern.edu EMAIL

    CALENDAR McCormick - Civil and Environmental Engineering