News & Events

Department Events

Events

• Jun

  1

  BME Seminar Series: Ning Wang, PhD

  McCormick - Biomedical Engineering Department

  4:00 PM L361 Technological Institute

  EVENT DETAILSmore info

  Ning Wang, PhD
  Leonard C. and Mary Lou Hoeft Professor
  University of Illinois at Urbana-Champaign
  Host: Professor Mark Johnson

  Title:
  “Force-induced direct gene transcription in living cells–

  Abstract:
  Despite decades of efforts, it remains elusive how physical forces influence gene expression in living cells and tissues. Here we show that gene transcription can be upregulated via force-induced direct chromatin stretching. Using green fluorescent protein (GFP) to label multiple sites in a chromatin domain and inserting a gene of interest between GFP spots, we were able to quantify the degree of chromatin stretching and transcription in a living cell. We found that transcription upregulation depended on force magnitude, force directionality, and the degree of chromatin stretching as well as tension in the cytoskeleton. Disrupting the force propagating pathway from the cytoplasm to the nuclear lamina abolished force-induced transcription. We discovered two nuclear proteins that transmitted force from nuclear lamins to the chromatin. We highlight our recent findings that forces and matrix mechanics regulate stem cell differentiation, early embryonic development, and growth and metastasis of malignant tumor-repopulating cells. Our findings demonstrate the critical roles of mechanotransduction in stem cell biology and cancer cell biology.

  more less

  TIME Thursday, June 1, 2017 at 4:00 PM - 5:00 PM

  LOCATION L361 Technological Institute    map it

  ADD TO CALENDAR

  CONTACT Jody Hoks    jody.hoks@northwestern.edu EMAIL

  CALENDAR McCormick - Biomedical Engineering Department

• May

  8

  Extending Care: A Conversation about Conservation and Futurity

  Block Museum of Art

  6:00 PM Block Museum of Art, Mary and Leigh

  EVENT DETAILSmore info

  The Center for Scientific Studies in the Arts is a collaboration between the Art Institute of Chicago and materials science-related departments at Northwestern University to pursue objects-based and objects-inspired scientific research. Materials research benefits ongoing work in conservation, archaeology, art history, and curatorial scholarship.

  Learn how the Center uses materials research to care for art objects in sustainable, innovative ways with Maria Kokkori, Senior Scientist in the Center for Scientific Studies in the Arts. She will be in conversation with Corey Byrnes, Northwestern Associate Professor of Chinese Culture and co-founder/co-director of the Environmental Humanities Workshop in Kaplan Humanities Center.

  This event is presented by the McCormick School of Engineering and Applied Science in conjunction with exhibition Actions for the Earth: Art, Care & Ecology.

  Register Now

  more less

  TIME Wednesday, May 8, 2024 at 6:00 PM - 7:30 PM

  LOCATION Block Museum of Art, Mary and Leigh    map it

  ADD TO CALENDAR

  CONTACT Block Museum of Art    block-museum@northwestern.edu EMAIL

  CALENDAR Block Museum of Art

• Jun

  10

  Northwestern Engineering PhD Hooding and Master's Degree Recognition Ceremony

  McCormick School of Engineering and Applied Science

  9:00 AM Welsh-Ryan Arena

  EVENT DETAILSmore info

  McCormick School of Engineering PhD Hooding and Master’s Degree Recognition Ceremony

  more less

  TIME Monday, June 10, 2024 at 9:00 AM - 11:00 AM

  LOCATION Welsh-Ryan Arena   

  ADD TO CALENDAR

  CONTACT Amy Pokrass    amy.pokrass@northwestern.edu EMAIL

  CALENDAR McCormick School of Engineering and Applied Science

• Jun

  10

  Northwestern Engineering Undergraduate Convocation

  McCormick School of Engineering and Applied Science

  2:00 PM Welsh-Ryan Arena

  EVENT DETAILSmore info

  McCormick School of Engineering Undergraduate Convocation

  more less

  TIME Monday, June 10, 2024 at 2:00 PM - 4:00 PM

  LOCATION Welsh-Ryan Arena   

  ADD TO CALENDAR

  CONTACT Amy Pokrass    amy.pokrass@northwestern.edu EMAIL

  CALENDAR McCormick School of Engineering and Applied Science