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  • Jun
    2

    BME Seminar Series: Rudolf Fuchshofer, PhD

    McCormick - Biomedical Engineering Department

    4:00 PM L361 Technological Institute

    EVENT DETAILSmore info

    Rudolf Fuchshofer, PhD
    Eshback Visiting Scholar Lecture
    Assistant Professor for the Institute of Human Anatomy and Embryology
    Universität Regensburg
    Prof. Dr. Rudolf Fuchshofer's undergraduate work was done at the University of Saarbrücken and at the University of Erlangen-Nürnberg while his graduate work was done at the University of Erlangen-Nürnberg. After graduation he moved to the University of Regensburg to join the group of Ernst Tamm. He is currently here on sabbatical working with Prof. Mark Johnson. His main research interests are the molecular functions of growth factors in the pathogenesis of glaucoma.

    Thursday, June 2nd
    4:00-5:00PM, Tech L361
    Host: Professor Mark Johnson

    Title:
    “Pathogensis of Glaucoma: Growth Factor Mediated Alterations to the Aqueous Humor Outflow Pathway–

    Abstract:
    The critical risk factor for optic nerve damage in primary open-angle glaucoma (POAG) is increased intraocular pressure (IOP) caused by an increased resistance to aqueous humor outflow in the trabecular meshwork outflow pathway. The molecular pathogenesis of this increased resistance has not been identified, but growth factors like TGF-β2 and CTGF may be involved, which are found in higher amounts in the aqueous humor of glaucomatous patients. We have developed a mouse model of POAG by an eye-specific overexpression of CTGF. This model shows elevated IOP and loss of axons from the optic nerve. The axon loss is accompanied by a disruption of the homeostatic balance of
    growth factors in the retina and by a reactivation of astrocytes in the optic nerve and by a structural modification of the peripapillary sclera. This model also allows us to explore the molecular interactions in the outflow pathway that cause elevated outflow resistance and IOP. We are confident that a continuous investigation of the biology in the eyes of CTGF-overexpressing mice will provide
    further ideas and concepts that will help to unveil the pathogenesis of POAG.

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    TIME Thursday, June 2, 2016 at 4:00 PM - 5:00 PM

    LOCATION L361 Technological Institute    map it

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    CONTACT Stephanie Hellenga Waninger    stephaniewaninger@northwestern.edu EMAIL

    CALENDAR McCormick - Biomedical Engineering Department

  • May
    8

    Extending Care: A Conversation about Conservation and Futurity

    Block Museum of Art

    6:00 PM Block Museum of Art, Mary and Leigh

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    TIME Wednesday, May 8, 2024 at 6:00 PM - 7:30 PM

    LOCATION Block Museum of Art, Mary and Leigh    map it

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    CONTACT Block Museum of Art    block-museum@northwestern.edu EMAIL

    CALENDAR Block Museum of Art

  • Jun
    10

    Northwestern Engineering PhD Hooding and Master's Degree Recognition Ceremony

    McCormick School of Engineering and Applied Science

    9:00 AM Welsh-Ryan Arena

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    TIME Monday, June 10, 2024 at 9:00 AM - 11:00 AM

    LOCATION Welsh-Ryan Arena   

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    CONTACT Amy Pokrass    amy.pokrass@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science

  • Jun
    10

    Northwestern Engineering Undergraduate Convocation

    McCormick School of Engineering and Applied Science

    2:00 PM Welsh-Ryan Arena

    EVENT DETAILSmore info

    TIME Monday, June 10, 2024 at 2:00 PM - 4:00 PM

    LOCATION Welsh-Ryan Arena   

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    CONTACT Amy Pokrass    amy.pokrass@northwestern.edu EMAIL

    CALENDAR McCormick School of Engineering and Applied Science