BME 395: Bioelectronics

Quarter Offered

Spring : TTh 9:30am-10:50am ; Rivnay, Rogers




Development and design of sensors, stimulators, and their medical devices for bio-integrated electronics. Materials design and fabrication of passive and active components for sensitive, multimodal, and robust wearable and implantable devices.


First year graduate students or upper level undergraduates. No formal prerequisites, however, core engineering concepts and basic understanding of biomaterials or physiology is helpful.


BME 395 covers the materials, device, and some systems level design of bioelectronics for wearable and implantable applications. Significant focus will be placed on the characteristics at the biotic/abiotic interface as they relate to immune response/device longevity, and on sensing/stimulation efficacy. Materials/form factor design will be addressed from the perspective of new concepts in bioelectronics for multimodal wearable patches and implanted probes for diagnostic and therapeutic applications. The course includes one weekly assessments, readings and discussions, a mid-term exam, and a final group presentation and paper on current leading-edge research topics in bioelectronics.

A parallel lab course (0.34 units, limited enrollment) will be offered; separate registration required, students registering for the lab must be registered for the lecture. This lab course includes 3 lab modules on biosignal acquisition and analysis, microfabrication and impedance measurements, and devices and analysis of multi-modal signals for gait analysis. Assessments include lab reports after each module, and presentations during the lecture course.


  • Biochemical/bioanalyte sensing
  • Biophysical sensing
  • Electrophysiological sensing
  • Impedance monitoring
  • Stimulation/Electroceuticals
  • Immune response and signal transduction
  • Novel form factors
  • New active materials
  • Transient electronics
  • Active recording/integration
  • Applications in wearables/rehabilitation
  • Optogenetics
  • Bioethics and regulatory, policy and security concerns


No required textbook. Readings will be provided or are feely available through NU.